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What is the difference between nephrolithiasis and soft tissue calcification?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

The findings of my 12 year old daughter's x-ray showed a cluster of 3 mm density overlying the right kidney, which may represent soft tissue calcification versus nephrolithiasis. I would like to get a clear understanding of the difference between soft tissue calcification and nephrolithiasis. Thank you

Answered by Dr. Krishna Somani

Education:

MBBS

Professional Bio:

Dr. Krishna Somani is a Nephrologist with extensive years of clinical experience, currently pursuing his DM in Nephrology to advance his expertise in kidney care. He specializes in diagnosing and managing kidney diseases, performing diagnostic tests, and guiding patients through comprehensive treatment plans. Dr. Somani is committed to improving renal health outcomes through evidence-based care, patient education, and a compassionate, individualized approach to treatment.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

  • Nephrolithiasis means kidney stones and soft tissue calcification means any part of renal parenchyma gets high deposits of calcium and show up in x-ray.
  • I want to know the reason for x-ray done.
  • Is she having pain in the flank or burning sensation in urine or fever or vomiting or any other urinary complaints? If yes, then we should straight away do an ultrasound to confirm these findings.

For further information consult a nephrologist online.

Patient's Query

Thank you doctor,

She was having trouble with constipation and thus the x-ray was taken. We are seeing a nephrology specialist next week. She has not had blood in urine or burning sensation or fever. To confirm, are you saying that these two are separate things?

Answered by Dr. Krishna Somani

Education:

MBBS

Professional Bio:

Dr. Krishna Somani is a Nephrologist with extensive years of clinical experience, currently pursuing his DM in Nephrology to advance his expertise in kidney care. He specializes in diagnosing and managing kidney diseases, performing diagnostic tests, and guiding patients through comprehensive treatment plans. Dr. Somani is committed to improving renal health outcomes through evidence-based care, patient education, and a compassionate, individualized approach to treatment.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome back to icliniq.com.

  • Yes, soft tissue calcification can be due to many causes like nephrocalcinosis (calcium deposit in kidney) or some calcified papillae or some medications or in very initial stages of stone formation.
  • X-ray is a very preliminary study to differentiate all this. It can only confirm a well formed stone of size more than around 5 mm to 10 mm and above.
  • It will be a good idea to visit a nephrologist for full evaluation. A plain CT KUB (scan of kidneys, ureters and bladders) will settle all queries.
  • But, considering her age, we also have to think about radiation exposure. Hence, I recommend a simple USG KUB.

Revert back with the report to a nephrologist online.

Medically reviewed by iCliniq medical review team
Published At September 22, 2016
Reviewed At April 13, 2025

Education:

MBBS

Professional Bio:

Dr. Krishna Somani is a Nephrologist with extensive years of clinical experience, currently pursuing his DM in Nephrology to advance his expertise in kidney care. He specializes in diagnosing and managing kidney diseases, performing diagnostic tests, and guiding patients through comprehensive treatment plans. Dr. Somani is committed to improving renal health outcomes through evidence-based care, patient education, and a compassionate, individualized approach to treatment.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

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Companion

X-ray Findings: Kidney Stones vs. Soft Tissue Calcification Companion

How it works

An X-ray showing density near the kidney can indicate either kidney stones (nephrolithiasis) or soft tissue calcification. This section explains the differences and what they mean.

1

Kidney
Stones

2

X-ray
Findings

3

Calcification
Causes

4

Imaging
Limits

5

Next
Steps

6

Consulting
Nephrologist

This information is based on general medical guidance. It is not a substitute for professional medical advice; consult a qualified clinician.

Always consult a doctor before taking medication; self-medication carries serious health risks. Take exact prescribed doses, and never start, change, or stop treatment without medical supervision.

Education:

MBBS

Professional Bio:

Dr. Krishna Somani is a Nephrologist with extensive years of clinical experience, currently pursuing his DM in Nephrology to advance his expertise in kidney care. He specializes in diagnosing and managing kidney diseases, performing diagnostic tests, and guiding patients through comprehensive treatment plans. Dr. Somani is committed to improving renal health outcomes through evidence-based care, patient education, and a compassionate, individualized approach to treatment.

This doctor is not available for online consultations on the platform anymore.

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