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Will Loratadine cure delayed ejaculation caused due to SSRI?

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Patient's Query

Hi doctor,

I am a 28-year-old male. I read an article in which Loratadine has been used to treat delayed ejaculation caused by SSRI. I have delayed ejaculation caused by Escitalopram 20 mg (taken for obsessive-compulsive disorder). I would like to know the mechanism of action of Loratadine in improving ejaculation. Please help.

Thank you.
Answered by Dr. Yousef Abbas

Education:

Medical Doctor Andrology and Sexual Medicine

Professional Bio:

Dr. Yousef Abbas is a specialist in andrology and sexual medicine, with extensive training completed during his residency. As a former Head of Staff Doctor, he brings strong leadership and clinical expertise in diagnosing and treating male reproductive and sexual health disorders. Dr. Abbas is committed to providing compassionate, evidence-based care, focusing on improving patients’ quality of life through advanced therapies and personalized treatment plans.

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Hi,

Welcome to icliniq.com.

You can continue taking SSRI (selective serotonin reuptake inhibitor) as prescribed by your doctor. I understand your situation that it is not pleasant to have delayed or no ejaculation due to SSRI. On the other hand, imagine all the paralyzed men or those men who do not masturbate due to religious reasons. They also go through this situation.

I also heard about Loratadine, and I strongly warn you. Escitalopram can prolong the QT time of your heart. For men, it should be less than 450 mg. Antihistamines like Loratadine can make this situation worse, and in some men, it can cause a life-threatening condition. I have never met anyone on SSRI who used Loratadine with success. I can understand your situation, and we must accept difficult things.

I hope this helps.

Please revert in case of further queries.

Thank you.

Medically reviewed by Dr. K. Shobana
Published At January 4, 2021
Reviewed At December 4, 2025

Education:

Medical Doctor Andrology and Sexual Medicine

Professional Bio:

Dr. Yousef Abbas is a specialist in andrology and sexual medicine, with extensive training completed during his residency. As a former Head of Staff Doctor, he brings strong leadership and clinical expertise in diagnosing and treating male reproductive and sexual health disorders. Dr. Abbas is committed to providing compassionate, evidence-based care, focusing on improving patients’ quality of life through advanced therapies and personalized treatment plans.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Yousef Abbas
Dr. Yousef Abbas

Andrology

Education:

Medical Doctor Andrology and Sexual Medicine

Professional Bio:

Dr. Yousef Abbas is a specialist in andrology and sexual medicine, with extensive training completed during his residency. As a former Head of Staff Doctor, he brings strong leadership and clinical expertise in diagnosing and treating male reproductive and sexual health disorders. Dr. Abbas is committed to providing compassionate, evidence-based care, focusing on improving patients’ quality of life through advanced therapies and personalized treatment plans.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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