Can a decrease in eGFR rate be a cause for concern?

Question

Hello doctor,

I am a 41-year-old woman with no diabetes or high blood pressure. In a recent blood test, my eGFR was 63.44 mL/min/1.73m², and my creatinine was 90 nmol/L. All other renal function tests (urea, potassium, sodium, bicarbonate, and chloride) are within normal range. In the lab results report, it says "mild decrease" of renal function as the eGFR is 63 mL/min. Is this a cause for concern?

Kindly guide.

Answer 1

Hello,

Welcome to icliniq.com

I read your query and understand your concern regarding your GFR (glomerular filtration rate) level. So, as I can see in your reports (attachment removed to protect patient’s identity), your creatinine level is normal along with other parameters. GFR depends on many factors, like age, muscle mass, weight, and amount of protein intake. The formula used to calculate GFR is not very reliable. To confirm whether it is a natural reduction of GFR with age or if it is due to kidney issues, you need to get your cystatin C level checked through blood. Moreover, get the urine protein creatinine ratio to look for protein leakage in urine. An ultrasound of the kidneys to rule out structural changes in the kidneys. I hope this helps. Kindly revert in case of any further queries.

I hope this helps.

Thank you.

Answer 2

Hello,

Welcome back to icliniq.com

It is mildly raised; do not worry about it. High BMI (body mass index) leads to raised ESR (erythrocyte sedimentation rate). I would advise you to work on your diet and lifestyle to lose weight. Many things would be taken care of if you do that.

I hope I cleared all your doubts.

Thank you.