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Is injection Penidure LA safe during pregnancy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

Initially, my wife was having few joint pains in her knees and shoulder. Last year, she was diagnosed with high ASO level in blood with 800 (positive). At that time the medicine physician has prescribed her to inject Penidure LA12 (Benzathine Penicillin) injection at every interval of 21 days for at least five years. Accordingly, since then my wife is continuing with Penidure LA12 injection till date and by now she has already completed two years of Benzathine Penicillin injection. Presently, a month back, her latest blood report the ASO level is reported negative with 175. Also, now my wife is 3 months pregnant and is under the supervision of a gynecologist.

The gynecologist has prescribed her with Susten SR 300 two tablets per day intravaginally and ALL-9 one tablet after food at night. Also, the gynecologist advised her to continue with Penidure LA12 and having the opinion that Penidure LA12 is safe during pregnancy and may be continued. Shall I continue her to inject Penidure LA12 injection during her present pregnancy stage? Or should I stop it? And also let me know, whether this injection will have any adverse effects on the baby. Lastly, for how many years actually this injection has to be taken by her? She has already completed two years. Thank you. Looking for your advice at the earliest.

Answered by Dr. Radhakrishnan Nair Bhaskaran

Education:

MBBS

Professional Bio:

Dr. Radhakrishnan Nair Bhaskaran is a well-experienced Obstetrics and Gynecologist with 36 years of clinical experience. He completed his MBBS from Karnataka University in 1988. He then did his DA from the University of Mysore in 1991. He then completed his DGO from the College of Physicians and Surgeons of Mumbai in 2008. He is currently working at Andro and Gynecare Clinic, Cochin, Kerala.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

Injection Penidure LA (Benzathine penicillin) is a long acting Penicillin given to your wife for increased anti-streptolysin O (ASO) titer, to prevent inflammatory disorders. It is safe during pregnancy compared to other antibiotics. Since, she is symptom free she should be continuing the injection. As you have not mentioned about her age and history of previous pregnancy or other medical problems, it is difficult to comment. I suggest you to consult a rheumatologist who will evaluate her and do the needful.

Patient's Query

Hello doctor,

My wife is 30 years old and this is her first pregnancy. Does the injection Penidure LA12 affect my wife as well baby? There is no medical history as such. Please guide.

Answered by Dr. Radhakrishnan Nair Bhaskaran

Education:

MBBS

Professional Bio:

Dr. Radhakrishnan Nair Bhaskaran is a well-experienced Obstetrics and Gynecologist with 36 years of clinical experience. He completed his MBBS from Karnataka University in 1988. He then did his DA from the University of Mysore in 1991. He then completed his DGO from the College of Physicians and Surgeons of Mumbai in 2008. He is currently working at Andro and Gynecare Clinic, Cochin, Kerala.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

Let her continue the injection and meanwhile take a second opinion from a rheumatologist.

Medically reviewed by iCliniq medical review team
Published At May 26, 2016
Reviewed At January 31, 2024

Education:

MBBS

Professional Bio:

Dr. Radhakrishnan Nair Bhaskaran is a well-experienced Obstetrics and Gynecologist with 36 years of clinical experience. He completed his MBBS from Karnataka University in 1988. He then did his DA from the University of Mysore in 1991. He then completed his DGO from the College of Physicians and Surgeons of Mumbai in 2008. He is currently working at Andro and Gynecare Clinic, Cochin, Kerala.

This doctor is not available for online consultations on the platform anymore.

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Decision Helper
Benzathine Penicillin in Pregnancy After Rheumatic Fever: Safety Decision Helper

Is Penidure LA safe during your pregnancy?

This tool helps you understand factors related to continuing Benzathine Penicillin injections during pregnancy. It is based on common medical considerations.

For guidance only, not a diagnosis. Always consult your doctor for personalized medical advice.

Education:

MBBS

Professional Bio:

Dr. Radhakrishnan Nair Bhaskaran is a well-experienced Obstetrics and Gynecologist with 36 years of clinical experience. He completed his MBBS from Karnataka University in 1988. He then did his DA from the University of Mysore in 1991. He then completed his DGO from the College of Physicians and Surgeons of Mumbai in 2008. He is currently working at Andro and Gynecare Clinic, Cochin, Kerala.

This doctor is not available for online consultations on the platform anymore.

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