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Can long term use of Levobren cause death?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I am writing about my mother who died 22 days back at the age of 76. For nearly ten years, she suffered from bronchiectasis and was treated with Cortisone. Five years back, because of a general illness (insomnia, tremors and loss of appetite) we went to a few specialists such as dietician and homeopathy doctor. After several failures, he prescribed the Levobren that my mother took in the dose of 15 drops per day. My mother took the drug continuously for a year and a half. After six months from beginning, she could not move the fingers of her right hand and this paresis gradually extended to the arm. In addition to this, she spent most of the day sleeping and she was in a state of mental confusion with low emotional and impulse control. After a geriatric hospitalization last year, it was denied that she suffered from Alzheimer's and was recommended a neurological examination. The neurologist, seeing that she was taking the Levobren from three years, was alarmed and suspended it. My mother was hospitalized in the neurology department where she was diagnosed of motor neuron disease. We decided to start a course of physiotherapy which initially seemed to give results, but then the paresis started to extend from the arm to the right leg, while the left part had no problem. Last month, due to a general illness, loss of swallowing reflex and aphonia she could not maintain an upright position and to presumed aspiration pneumonia, she was hospitalized and she died. Taking into account that by specialist examinations made after the first neurological examination no one has ever confirmed the motor neuron disease, and no one knew how to cure her since she was not included in the protocol of no diagnosis. I would wonder if all this could be caused from taking that drug. I am still clueless as to why my mother died?

Answered by Dr. Ambekar Sudheer

Education:

MBBS

Professional Bio:

Dr. Ambekar Sudheer is a highly experienced Neurologist specializing in Neurosurgery with extensive clinical expertise. He is proficient in diagnosing and treating complex neurological conditions and performing advanced surgical interventions to enhance patient outcomes. His areas of expertise include brain and spine surgeries, minimally invasive neurosurgical procedures, and comprehensive care for neurological disorders, ensuring holistic treatment and rehabilitation for patients.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com. Sorry to hear about your mother. Sluggishness, vomiting and sopor (abnormally deep sleep) are the common side effects. Also, long-term use may lead to dystonia. From the given information, I will not be able to exactly pinpoint the cause of death. However, I believe the treating neurologist did the right thing by stopping Levobren (Levosulpiride). Clinical examination and electroneuromyography (ENMG) are diagnostic for motor neuron disease (MND). I urge you to make sure that ENMG showed features of anterior horn cell disease. Besides this, an magnetic resonance imaging (MRI) of the spine should also have been done.

Medically reviewed by iCliniq medical review team
Published At March 17, 2016
Reviewed At June 20, 2024

Education:

MBBS

Professional Bio:

Dr. Ambekar Sudheer is a highly experienced Neurologist specializing in Neurosurgery with extensive clinical expertise. He is proficient in diagnosing and treating complex neurological conditions and performing advanced surgical interventions to enhance patient outcomes. His areas of expertise include brain and spine surgeries, minimally invasive neurosurgical procedures, and comprehensive care for neurological disorders, ensuring holistic treatment and rehabilitation for patients.

This doctor is not available for online consultations on the platform anymore.

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Companion

Levosulpiride Long-Term Neurological Side Effects Companion

How it works

Levosulpiride, often known by brand names like Levobren, is a medication that can have various effects, especially with long-term use. Understanding these effects is important for your health discussions.

1

About
Levosulpiride

2

Common
Effects

3

Long-Term
Concerns

4

Neurological
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5

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Neuron

6

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Consultation

This information is based on general medical guidance. It is not a substitute for professional medical advice; consult a qualified clinician.

Always consult a doctor before taking medication; self-medication carries serious health risks. Take exact prescribed doses, and never start, change, or stop treatment without medical supervision.

Education:

MBBS

Professional Bio:

Dr. Ambekar Sudheer is a highly experienced Neurologist specializing in Neurosurgery with extensive clinical expertise. He is proficient in diagnosing and treating complex neurological conditions and performing advanced surgical interventions to enhance patient outcomes. His areas of expertise include brain and spine surgeries, minimally invasive neurosurgical procedures, and comprehensive care for neurological disorders, ensuring holistic treatment and rehabilitation for patients.

This doctor is not available for online consultations on the platform anymore.

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