How long does it take for the insulin resistance level to reduce?

Hello,

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As you are trying to conceive and your insulin levels are pretty high. It looks like you have PCOS. This is a congenital condition, I mean it is a genetically programmed condition, you get it from your parents. When you suddenly put on weight, this cholesterol is converted into estrogen hormone. In your body too when fat, which is a store for tomorrow, is more than normal, this is converted to the hormone which tips the balance between FSH (from the brain) and the ovarian hormone. FSH (follicle-stimulating hormone) as the name suggests stimulates the follicle from the ovary, but once the follicle is big enough to ovulate, the FSH is suppressed by the same estrogen hormone from the ovary. But when the same estrogen hormone is coming from fat, the brain is confused and follicle growth stops early at a smaller follicle size and will not rupture, next scan you will see all these follicles as polycystic ovaries.

This is usually associated with obesity, irregular cycles, no periods for a few months, and later heavy periods with clots and fleshy masses, spotting on and off, thyroid abnormality, and prolactin problem indirectly.

You develop that extra pad of fat around the mid-segment of the body, especially the waist, thighs, and breasts, with no fat beyond the elbow and knees. Excessive body hair growth, hair fall, a dark shade over the lower half of the face, acne, oily face skin, black skin over the back of the neck, inner thighs, and under the surface of the breast. May have a family history of diabetes, especially father or his family.

This will not allow ovulation to occur at any time and so you cannot get pregnant, till treated. It also increases your chances of early pregnancy abortions. But this has a solution.

Once you reduce weight to the normal range, you will not need any medicine to get periods or to get pregnant and pregnancy will be healthy.

To reduce weight -

1. Avoid junk food, fast foods, and red meat, and reduce snacks in between meals.
2. Have low calories food, high proteins.
3. Regular exercise (especially for the waist and hip area), aerobics, yoga, and brisk walking (swing your hands well).

Kindly see if the following checklist of investigations is done.

1. Husband- Two semen analyses that are done four weeks apart preferably in an infertility center and blood sugars.
2. Wife - Blood sugars, thyroid profile, ultrasound scans to evaluate uterus, ovaries, and adnexa. Confirm tubal patency. Check with HSG (hysterosalpingography). Laparoscopy.

I hope this has helped you. Thank you.