HomeAnswersHematologymthfr mutationPlease interpret my breast ultrasound for enlarged lymph nodes and breast cancer.

Is inherited MTHFR gene mutation a risk factor for breast cancer and increased lymphocyte count?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Vinodhini J.

Published At July 30, 2020
Reviewed AtJuly 27, 2023

Patient's Query

Hello doctor,

I need help to understand the attached breast ultrasoud. I also have the MTHFR gene mutation inherited from both parents and want to know if it will affect my lymphocyte count to be high. I am taking Maxalt for migraines.

Hi,

Welcome to icliniq.com.

I have seen the attached report (attachment removed to protect patient identity).

MTHFR gene mutation is not an independent risk factor for breast carcinoma. The association between this gene mutation and breast malignancy is not fully understood. However, in your attached ultrasound, breast mass is not present. There is no malignant mass in the breast in the ultrasound report. So do not worry about breast cancer.

But if the mentioned nodule and enlarged lymph node persist for a few days, then biopsy can be taken for histopathology examination. Histopathology examination will be the best to diagnose the exact cause for that nodule and enlarged node. As far as the ultrasound report is concerned, do not worry about that.

Lymphocytes are mildly elevated. It could be due to viral inflammation as well. Repeat your CBC (complete blood count) after a few days and revert back.

I hope this helps.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri

Pathology

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