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Is it possible to desensitize myself to nickel?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I have been sensitized to nickel from a scalp adhesive for hair replacement. The bond had nickel sulfate. I did this for 10 years. I developed dermatitis or eczema in my brows and eyelids, etc. I have realized that since I have decreased my dietary nickel intake and stopped the bonding, my eczema has greatly improved, but if I do eat foods high in nickel, I get hit. Even two years after I stopped the hair bonding. Is it possible to desensitize myself to nickel?

Kindly help.

Hi,

Welcome to icliniq.com.

I understand your concern and will try to help you with it.

I have gone through your case. Well, desensitization is a process in which we gradually expose a patient to an allergen until the patient develops a tolerance for it. To date, it is being considered as a therapy for many conditions, such as penicillin sensitivity or rhinitis, and in eczema (for diagnostic purposes). But specifically for nickel, no studies have been conducted for it. Means there is no specific protocol of administration. Nickel is found in many objects, and even when patients develop nickel dermatitis, there are cross-reactivities with other products, too. In short, desensitization is done for a few specific conditions with strict protocols.

I hope this helps.

You can always reach me at icliniq.com.

Thank you.

Patient's Query

Hi doctor,

Thank you for the reply.

I appreciate that. Is it possible that dermatitis will simply go away on its own over time? I was exposed to the adhesive for 10 years. Can it take a long time to go away? It has been two years since I stopped the adhesive. Can it go away? Also, my platelet count was low, in the 113 to 130 range. That could have been from the sensitization as well.

Hi,

Welcome back to icliniq.com.

I read and understand your concern.

First of all, there is no correlation between low platelets and allergies, eczema or sensitization. It could be due to some other cause, such as a viral illness like the flu or some drugs. The best way is to monitor the count by doing a platelet count every other day. Then, once you develop an allergy or hyperactive response to an allergen, the best treatment is to decrease the exposure because subsequent exposure may result in a worse response.

As long as we have good or strong immunity, this will persist and will not go away until we decrease the response by taking immunosuppressant drugs, and immune cells are no longer available to react against these allergens. So, decreasing exposure to allergens or immunosuppressant drugs is its management. However, very rarely, patients may not develop any reaction after the first one, but this is only a rare thing. Remember, there is no hard and fast rule. Every single patient has a different immune response. We need to understand that.

I hope this helps.

Please feel free to reach out in case of further queries.

Thank you.

Answered byDr. Shanza Ikram

Medically reviewed byiCliniq medical review team

Published At June 22, 2018
Reviewed AtMarch 5, 2026

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