What could cause a missed period after unprotected sex despite a negative pregnancy test?

Hello,

Welcome to icliniq.com.

I went through your query.

Missing periods may not be due to just pregnancy. Pregnancy is fully ruled out as beta hCG (human chorionic gonadotropin) has confirmed that there is no pregnancy.

From your history, I presume she has PCOD (polycystic ovary disorder),

This is a congenital condition. I mean it is a genetically programmed condition, you get it from your parents. When you suddenly put on weight, this cholesterol is converted into estrogen hormone. In your body when fat is more than normal, this is converted to the hormone that tips the balance between the follicle-stimulating hormone (from the brain) and the ovarian hormone. FSH (follicle-stimulating hormone) as the name suggests stimulates the follicle from the ovary, but once the follicle is big enough to ovulate, the FSH is suppressed by the same estrogen hormone from the ovary. But when the same estrogen hormone is coming from fat, the brain is confused and follicle growth stops early at a smaller follicle size and will not rupture. In the next scan, you will see all these follicles as polycystic ovaries.

This is usually associated with obesity, irregular cycles, no periods for a few months, and later heavy periods with clots and fleshy masses, spotting on and off, thyroid abnormality, and prolactin problems indirectly.

Excessive body hair growth, hair fall, a dark shade over the lower half of the face, acne, oily face skin, black skin over the back of the neck, inner thighs, and under the surface of the breast.

This will not allow ovulation to occur at any time so you cannot get pregnant, till treated. It also increases your chances of early pregnancy abortions. But this has a solution.

1. The weight should be under control. Once you reduce weight to the normal range, you will not need any medicine to get periods or to get pregnant and pregnancy will be healthy.

2. Do not fast.

3. Avoid junk food, fast foods, and red meat. Reduce snacks in between meals.

4. Have low-calorie food and high proteins.

5. Regularly exercise.

To have periods, I suggest she can take any of the birth control pills.

Kindly consult a specialist, talk with them, and take medicines with their consent.

Hope it helps.

Thanks and regards.