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Can I take Phentermine along with Cymbalta?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I take Cymbalta 60 mg for depression and Trazodone 100 mg for sleep. Can I take Phentermine for weight loss without problems of serotonin syndrome?
Answered by Dr. Srivastava Sumit

Education:

MBBS

Professional Bio:

Dr. Sumit Srivastava is a skilled General Practitioner and Family Physician with extensive clinical experience. He is also an expert in Internal Medicine, dedicated to providing comprehensive healthcare for individuals and families. Known for his patient-focused approach, he ensures quality care and long-term wellness. His expertise includes managing lifestyle disorders, chronic illnesses, and preventive healthcare, with a strong emphasis on accurate diagnosis and holistic treatment.

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Hi,

Welcome to iCliniq.com. Phentermine is a medication that is typically used for a short period of time, usually a few weeks, as an adjunctive treatment for weight reduction in patients with an initial body mass index (BMI) equal to or greater than 30 kg/m². Cymbalta, which contains the active ingredient duloxetine, has a serious interaction with Phentermine. When taken together, they can increase the toxicity of each other and pose a potential risk for serious or life-threatening interactions. Additionally, there is a risk of developing serotonin syndrome, which is a condition caused by excessive levels of serotonin in the body and can be life-threatening. Therefore, based on these interactions and risks, I would not recommend the simultaneous use of Cymbalta and Phentermine. Please let me know if you have any further questions or concerns.

Medically reviewed by iCliniq medical review team
Published At June 7, 2016
Reviewed At July 22, 2024

Education:

MBBS

Professional Bio:

Dr. Sumit Srivastava is a skilled General Practitioner and Family Physician with extensive clinical experience. He is also an expert in Internal Medicine, dedicated to providing comprehensive healthcare for individuals and families. Known for his patient-focused approach, he ensures quality care and long-term wellness. His expertise includes managing lifestyle disorders, chronic illnesses, and preventive healthcare, with a strong emphasis on accurate diagnosis and holistic treatment.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

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Phentermine and Cymbalta Interaction Risk Decision Helper for Weight Loss Management

Considering Phentermine with other medications?

This quick check helps you understand potential risks when combining phentermine with certain antidepressants.

This tool provides general information and is not a substitute for professional medical advice. Medications should be taken after consulting a physician. The dosages will be prescribed by the physician. Do not alter, start, or stop medications without consulting a healthcare professional.
Dr. Srivastava Sumit
Dr. Srivastava Sumit

Internal Medicine

Education:

MBBS

Professional Bio:

Dr. Sumit Srivastava is a skilled General Practitioner and Family Physician with extensive clinical experience. He is also an expert in Internal Medicine, dedicated to providing comprehensive healthcare for individuals and families. Known for his patient-focused approach, he ensures quality care and long-term wellness. His expertise includes managing lifestyle disorders, chronic illnesses, and preventive healthcare, with a strong emphasis on accurate diagnosis and holistic treatment.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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