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What does polycythemia (JAK 2 negative) mean?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am diagnosed with polycythemia (JAK 2 negative). I need more knowledge; my BM and JAK2 studies are within normal limits.

Kindly help.

Thank you.
Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

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Hello,

Welcome to icliniq.com.

Your present CBC report is not suggestive of polycythemia, especially polycythemia vera, which is a blood cancer condition (attachment removed to protect patient identity). Your JAK 2, EXON 12 study and bone marrow report are normal as per history. So, polycythemia vera is much less likely. Your high hemoglobin could be due to a secondary polycythemia cause. Secondary polycythemia is a purely benign condition. The causes for that include respiratory problems, cardiac problems, smoking, severe dehydration, etc.

I suggest you drink lots of water, especially three liters per day. Avoid smoking if you have a habit. It is advisable to repeat the CBC after a few days.

I hope this helps.

Thank you.

Medically reviewed by Dr. Divya Banu M
Published At June 10, 2019
Reviewed At March 2, 2026

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. Divya Banu M is a dedicated Dental Surgeon with valuable clinical experience. She specializes in the diagnosis, prevention, and treatment of various diseases and conditions affecting the oral cavity. With a gentle and patient-centered approach, she is committed to promoting oral health and enhancing smiles through quality dental care. Her areas of expertise include restorative dentistry, preventive dental care, and cosmetic dental procedures.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri

Pathology

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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