Polycythemia

Polycythemia is a condition where the volume percentage of red blood cells in the blood (hematocrit) is elevated. It can be either caused due to an increase in the number of red blood cells or a decrease in the volume of plasma. The treatment is done by phlebotomy, that is the removal of blood from the circulation.

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What is the reason for recurrent diarrhea, nausea and extreme fatigue?

Query: Hello doctor, I am having some recurrent symptoms: • Nausea (intermittent). • Diarrhea. • Extreme fatigue (daily). • Severe insomnia even on Ambien (falling asleep faster but still wake up three times a night, and I always wake up exhausted). • Muscle weakness especia...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to icliniq.com. I have read the attached reports. (attachment removed to protect patient identity). The red blood cells count, hemoglobin and HCT (hematocrit) are slightly raised. So secondary polycythemia seems most likely. The smoking habit, heart problem, chronic lung disease...  Read Full »

Is anisopoikilocytosis dangerous?

Query: Hello doctor, I am a 53 year old woman diagnosed with polycythemia vera (PV) three years ago. I am being treated with phlebotomy. I have fatigue at times, as well as some thinking impairment at times. Over time I have developed various anomalies in my blood test results, which my doctor explained as...  Read Full »


Dr. Prakash H Muddegowda

Geriatrician, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. Based on your query regarding polycythemia, my opinion is as follows: Due to nutritional deficiencies, secondary to excessive RBC (red blood cell) production and also mild dyserythropoiesis (defective development of red blood cells), you can find microcytic hypochromic...  Read Full »

I am diagnosed with polycythemia (JAK 2 negative). Kindly explain.

Query: Hello doctor, I am diagnosed with polycythemia (JAK 2 negative). I need more knowledge, my BM and JAK 2 studies are within normal limit.  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to icliniq.com. Your present CBC report is not suggestive of polycythemia especially polycythemia vera which is blood cancer condition (attachment removed to protect patient identity). Your JAK 2, EXON 12 study and bone marrow report is normal as per history. So polycythemia vera is...  Read Full »

I was recently diagnosed with polycythemia. Would it be due to smoking?

Query: Hello doctor,I was recently diagnosed with polycythemia due to increased red cell count of 5.28x10^12/L, HCT 0.466, and hemoglobin of 161 g/l. I stopped smoking two weeks ago. Six months ago, when I started to smoke, I smoke only four cigarettes per day. Would the high red cell count be a case of se...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to the icliniq.com. You have polycythemia. It can be primary or secondary polycythemia. The primary polycythemia is the cancer of bone marrow, which means myeloproliferative neoplasm. However your total WBC count and platelet count within range. So the chance of primary polycythemia...  Read Full »

What can be the reason for elevated RBC, Hb and Hct?

Query: Hi doctor, I am a 34 year old female. I have been itching all over for months and constantly covered with bruises, petechiae and livedo reticularis. I was diagnosed with erythromyalgia. I also have severe bone pain. My blood work came back with elevated RBC, Hb, Hct, low alkaline phosphate, low BUN...  Read Full »


Dr. Prakash H Muddegowda

Geriatrician, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: The elevated hemoglobin, red blood cell count and hematocrit signify polycythemia. Elevated Vitamin B12 level is one of the markers of myeloproliferative disorder. I would strongly think of polycythemia vera. Other valu...  Read Full »

Is there any association between polycythemia and hemochromatosis?

Query: Hello doctor, Is there an association between polycythemia and hemochromatosis? I have a high Hb of 18 and hematocrit of 51 %. I am a student and found to have incidental polycythemia. I tested for all myeloproliferative neoplasm and bone marrow biopsy is negative for MPN. However, I was tested to ...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hello, Welcome to icliniq.com. Usually, in hemochromatosis, storage iron is increased, that is serum ferritin. So you can investigate with serum ferritin as well. If you have myeloproliferative neoplasm like polycythemia, then usually it can be clear from bone marrow study and JAK2 mutation. It co...  Read Full »

What does high hemoglobin level indicate?

Query: Hello doctor, I am so worried. I had a blood test and my hemoglobin is 16 g/dl (9.9 mmol/l) and hematocrit is 46 PTC. I am female, 39, and healthy. My white blood cells, platelets, and thrombocytes are in normal middle range. Is a bit high hemoglobin sign of some sickness? What to do next?  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hi, Welcome back to icliniq.com. So, actually, your hemoglobin level is borderline high and not low. So, you are not having anemia. You are probably thinking about polycythemia. But as your hemoglobin is not much elevated and your total WBC count with platelet count are within range, no need to wo...  Read Full »

Hemoglobin and RBC count are high. What is the reason?

Query: Hello doctor, I had a blood test today and the results show hemoglobin is 18.05 and the RBC are 5.8 and hematocrit is 42 %. Should I be worried?   Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. Your hemoglobin and RBC are certainly high. So your diagnosis can be polycythemia. It can be secondary erythrocytosis for which you can investigate with EKG and chest X-ray to rule out the cardiac or respiratory cause. If you have any dehydration or prolonged fasting hi...  Read Full »

If I quit smoking, will my RBC, hemoglobin, and PCV levels come back to normal?

Query: Hello doctor, I am suffering from hypertension since few years, and I am currently on medication Telmisartan. I am an alcoholic and smoker, and I smoke approximately 15 cigarettes a day for the last five years. My current CBC report suggests high RBC, hemoglobin, and PCV. Though it reduced slightly...  Read Full »


Dr. Parth R Goswami

Family Physician, General Practitioner, Hematologist, Pathologist

Answer: Hi, Welcome to icliniq.com. I have gone through your attached reports (attachment removed to protect patient identity). The diagnosis is polycythemia. Polycythemia can be secondary or primary. Secondary polycythemia occurs because of hypoxia, which activates the oxygen sensor and more erythropoiet...  Read Full »

Is it possible to have low erythropoietin count and high RBC count together?

Query: Hello doctor, I am 27 years old male, 6 feet, and 180 lbs. I started a new job and the life insurance company wanted me to take a blood test. The results are attached. My blood test shows a low erythropoietin of 4.4 U/L (normal range 4.3 to 29) and high red blood cell count of 5.6x10^12/L (normal ...  Read Full »


Dr. Girish C Kamat

Internal Medicine Physician, Hematologist

Answer: Hello, Welcome to icliniq.com. Your hemogram and erythropoietin levels are normal. I would not evaluate you any further. They should not have asked for a hematology consultation, but if it is mandatory, get it done.  All the best and do well in your new job. For further queries consult a hematolog...  Read Full »

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