HomeAnswersInternal Medicineprocalcitonin as a biomarker of infectious diseasesHow does monitoring procalcitonin levels help with sepsis?

What is the correlation between procalcitonin and sepsis?

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Published At April 6, 2024
Reviewed AtApril 6, 2024

Patient's Query

Hello doctor,

I have heard about procalcitonin levels being associated with sepsis. Please provide personalized insights into how procalcitonin is related to sepsis, the normal levels, and how monitoring this biomarker is relevant for me based on my health history or specific concerns related to sepsis.

Kindly help.

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

Here is some general information about procalcitonin and sepsis:

  1. Procalcitonin and Sepsis: Procalcitonin is a protein produced by the thyroid gland and the immune system in response to infection. In sepsis (a potentially life-threatening condition caused by an infection), procalcitonin levels can rise rapidly as the body responds to the infection. Monitoring procalcitonin levels can help healthcare providers determine the severity of sepsis and guide treatment decisions.

  2. Normal Levels: The normal range for procalcitonin levels in the blood is generally considered to be less than two nanograms per milliliter (ng/mL). However, this can vary depending on factors such as age and underlying medical conditions.

  3. Relevance for Sepsis: If you have a history of sepsis or are at increased risk of developing sepsis (such as due to a weakened immune system or a chronic medical condition), monitoring procalcitonin levels may be relevant. Healthcare providers may use procalcitonin testing to help determine the appropriate course of treatment for sepsis, such as whether antibiotics are necessary or additional diagnostic tests or interventions are required.

  4. Relevance for Other Medical Conditions: Procalcitonin levels may also be relevant for other medical conditions, such as respiratory infections or cancer, as they can provide insight into the severity of the infection and help guide treatment decisions.

  5. Limitations: It is important to note that procalcitonin testing is not a substitute for clinical judgment and should be interpreted in the context of a patient's overall clinical presentation and laboratory findings. False positives or false negatives can occur, and additional diagnostic tests may be necessary to confirm a diagnosis of sepsis or other medical conditions.

I hope this information will help you.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Vandana Andrews
Dr. Vandana Andrews

General Practitioner

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