HomeAnswersUrologyprostatitisCan biopsy be done in a condition with a high PSA levels?

Is antibiotic treatment necessary to treat prostatitis?

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Published At May 13, 2022
Reviewed AtSeptember 5, 2023

Patient's Query

Hi doctor,

I am consulting you about a prostate gland problem. I am having a problem in passing urine, and there is a pain in the lower abdomen up to the scrotum and the testicles, but no fever yet. I saw the doctor a few days back, and he prescribed a blood test and my PSA level has been > 8 ng/dl. I have symptoms of prostatitis. Around five months back, a urologist did sonography and found a gland that was swollen, with scars on it (from older prostatitis) and a "harder" outer shell consistency. The doctor suggested that I take Ciprofloxacin 500 mg thrice daily for three weeks to avoid a full-fledged infectious syndrome and to drive the PSA value down. I was told that eventually, I should go for a biopsy too. My question is do I need to take the antibiotics treatment? What would be the criteria to apply to the decision? Can a urologist go for a biopsy under the present high PSA levels? Is there a chance that the PSA value will go down again, with or without antibiotic therapy? What is an evidence-based approach (best conduct) in this case?

Thank you for your guidance.

Hello,

Welcome to icliniq.com.

Prostatitis needs long-term antibiotic treatment if you have symptoms because of that. A biopsy is indicated in raised PSA (prostate-specific antigen) value if you have ruled out infection or any other benign causes for that. Yes, there are chances that the PSA value might go down if it is because of infection. Approach: First of all, we have to rule out prostatitis as a cause of your raised PSA. If there is confusion then it is better to go for multiparametric MRI (magnetic resonance imaging) of the prostate first. If it shows a chance of malignancy then better go for a biopsy. Again, as you said your urologist examined and found a hard gland which could be because of chronic prostatitis or malignancy. But if the whole gland is hard we would have expected a higher PSA level. The best approach right now for you would be to go for multiparametric MRI prostate.

Patient's Query

Hi doctor,

Thank you for your assessment and advice.

Just to add two more concerns. Can I practice biking under these circumstances, is there any risk? Can I use real lavender oil in my humidifier? Are there any adverse interactions of concern with the prostrate gland hormone system?

Hi,

Welcome back to icliniq.com.

If you have pain in the perineum because of prostatitis then it may increase during off-road biking as pressure is directly over the prostate. Lavender oil can be used.

Patient's Query

Thank you doctor for the reply,

In the search for indications of carcinoma of the prostate gland, an MRI exam was conducted, and below are the translated findings from the prostate report:

  1. There is a discrete enlargement of the prostate (1.57 x 1.77 x 2.16 inches; volume - 51 cm²) with an inhomogeneous internal structure, indicative of prostatic hyperplasia.

  2. An oval-shaped focal point is observed in the posterior region on the right side (9:00 AM position), measuring 0.39 x 0.19 inches. This focal point appears hypointense in T1 and T2 weighted images, mesointense in DWI, and ADC. It is not distinguishable from the normal prostate structure in the lower part. Prostate evaluation (PE) is recommended in this regard. Seminal vesicles appear normal, and the urinary bladder is adequately filled with fluid and has a smooth wall contour. No pathological enlargement of lymph nodes is observed in the imaged area. The inguinal region on both sides is unremarkable.

Evaluation: Prostate hyperplasia with suspicious focal point in the posterior right floor area, categorized as PI-RADS v.2.1 - 3.

It is worth noting that back in the 90s, I experienced prostatitis, possibly due to intensive biking. At that time, the urologist identified a scar on the surface of the prostate gland. I am curious whether the hyperplasia detected by the MRI could be linked to this unevenness or scar on the gland's surface. Regarding sharing the MRI images with you, could I provide screenshots or send the file to facilitate visualization on your end?

Thank you for your help and support. Kind regards.

Hello,

Welcome back to icliniq.com.

Your MRI suggests a PIRADS 1-3 score, which is not indicative of cancer itself. I would suggest that you wait and undergo follow-up with serial S.PSA tests every three months for the first year. If the PSA level increases, then you should consider a biopsy; otherwise, there is no need to proceed with one.

Thank you.

Regards.

Patient's Query

Thank you doctor for the reply,

I have successfully completed a new PSA test, and the results are presented in the attached documents. Could you please confirm the nature of the tumor identified by the multiparametric MRI on the prostate gland? Should I arrange for additional PSA tests every three months? Also, considering that the MRI was conducted without a contrast agent, how dependable is the PIRAD score?

Hello,

Welcome back to icliniq.com.

Your PSA appears to be under control. I do not believe it is the appropriate time for a biopsy. I would recommend continuing with S.PSA tests every three months for a year. After that, you could consider increasing the frequency to every six months and eventually transitioning to once a year. There is no need to worry at this moment.

Thank you.

Regards.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Praveen Pushkar
Dr. Praveen Pushkar

Urology

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