I have been suffering from psoriasis and noticed a swelling in my leg for the past few days. Why so?

Q. How to reduce swelling caused due to psoriasis?

Answered by
Dr. Dhepe Snehal Madhav
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Apr 27, 2023 and last reviewed on: Jun 12, 2023

Hello doctor,

I have diabetes and hypertension. I have had psoriasis for the past few years in my left ankle. Now I have noticed swelling in the same part of my leg for the past few days, which causes pain. Please suggest treatment. Please help.



Welcome to icliniq.com.

I request you attach a clinical picture so that I can guide you accordingly.

Thanks and regards.

Hello doctor,

Thanks for your reply.

I have attached the file. Please check.



Welcome back to icliniq.com.

I understand your concern.

I went through the image (the attachment is removed to protect the patient's identity). Psoriasis is a chronic inflammatory condition of the skin that presents with a scaly plaque with redness and fissures. In 25 % of cases, it can be itchy. There is a secondary bacterial infection associated with psoriasis. If localized, then topical treatment is sufficient enough to take care of it. It can be well controlled. Triggers are stress, environmental changes, trauma, and extremely cold weather. So, I suggest you do the following:

1. Avoid painkillers like Diclofenac and Ibuprofen as they are known to exacerbate psoriasis.

2. Apply Mupirocin (antibiotic) ointment twice daily during the daytime for 15 days.

3. Apply Physiogel (glycerin, ceramide) hypoallergenic lotion immediately after bath for one month.

4. Apply Topisal (Clobetasol and Salicylic Acid) 3 % ointment at night for ten days.

5. Avoid triggers.

6. Avoid stress.

7. Do yoga and practice relaxation techniques.

8. Avoid trauma and injury to the skin.

9. Do not scratch lesions.

10. Use good moisturizers to keep skin hydrated.

11. Keep sugar levels under control.

Kindly consult a specialist, talk with them, and take medicines with their consent.

Thanks and regards.

Hi doctor,

Thank you for the reply,

This is the present stage (see the attached picture). Now there is no swelling, but there is occasional itching. Is further treatment needed?



Welcome back to icliniq.com.

I understand your concern and query.

I saw the attached picture (the attachment is hidden to protect the patient's identity). I suggest you apply liquid Paraffin lotion in the daytime for 15 days. Kindly provide details for the below questions for a better understanding:

1. Is it oozing or burning, or do you have any pain?

2. Do you have issues with excess scratching and rubbing?

3. Is it tender to touch?

4. Does it bleeds on scratching?

Revert with answers to the questions.


Hi doctor,

Thank you for the reply,

I have only itching and pain occasionally.



Welcome back to icliniq.com.

I suggest you take the following:

1. Tablet Loratadine 10 mg once a day after breakfast for ten days (if itching).

2. Apply liquid Paraffin lotion in the daytime for 15 days.

3. Tablet Antoxid HC (Beta carotene, Zinc sulfate monohydrate, Selenium dioxide) once daily after breakfast for 30 days.

4. Avoid taking painkillers like Ibuprofen as it may aggravate psoriasis.

5. Avoid scratching and rubbing of lesions.

6. Apply Mupirocin ointment during the daytime for ten days (if pain), as it could be associated with a secondary bacterial infection.

7. Avoid stress or emotional trauma.

8. Avoid exposure to extreme weather conditions.

9. Keep the area moisturized.

10. Coconut oil or olive oil can be used to soothe lesions as a home remedy.

11. Wet wrap therapy can be used.

12. If oozing, apply Topisal 6 percent lotion (Clobetasol and Salicyclic acid) in the evening for ten days.

13. Moisturize the skin immediately after bath and three to four times daily with Cetaphil cream.

I hope this helps.

Kind regards.

Hello doctor,

Thank you.

I have attached the photos of the affected leg. No fluid secretion or itching. But the skin color is not normal. I am taking Antoxid HC for about three weeks. We have planned to go abroad and stay there for five months. Can you please prescribe medicines to use there in case of any relapse of the problem?



Welcome back to icliniq.com.

I understand your concern.

I went through the image (the attachment is removed to protect the patient's identity).

I suggest you apply liquid paraffin lotion during the daytime for 15 days and Mupirocin ointment during the daytime for 15 days.

Hope this helps.


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