HomeAnswersHematologymiscarriageI had thrombophilia panel test as I had two miscarriages. Do I need any treatment to get pregnant?

As I faced two miscarriages, I had thrombophilia panel test. Is there anything suspicious?

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Answered by

Dr. Kamal Kant Sahu

Medically reviewed by

iCliniq medical review team

Published At December 16, 2018
Reviewed AtFebruary 7, 2024

Patient's Query

Hi doctor,

I am a 36-year-old female. I had two chemical pregnancies this year, and I am childless. Due to my age, I decided to investigate more. The thrombophilia panel test results recommended me to see a hematologist. I have positive results (heterozygous) for MTHFR C677T, PAI 4G by 5G, AGT M235T, factor XIII Val34Leu, and fibrinogen 455 G by A. Will I need special treatment for a future pregnancy? Please help me.

Hi,

Welcome to icliniq.com.

I have reviewed your case. It seems that you had two miscarriages. So, you have to know a little detail about your condition and to understand thrombophilia. The risk of abortion is none to minimal in normal pregnancy, whereas intermediate and high in heterozygous and homozygous mutation, respectively.

In your case, as you have twice a pregnancy failure, I have two recommendations. Try to do the APLA test (antiphospholipid antibody workup) which is just an extension of the thrombophilia workup. During future pregnancy, usually in your case, we need to give some medications that can maintain your blood flow, and it can prevent the micro clot formation in the placental blood vessels, and hence the chances of abortion will decrease.

These drugs need to be prescribed by your hematologist (low molecular weight Heparin and Warfarin). You can discuss with your hematologist regarding the test suggested and about the drugs that may help you in future pregnancies.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Kamal Kant Sahu

Dr. Kamal Kant Sahu

Hematology

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