Patient's Query
Hi doctor,
I am a 36-year-old female. I had two chemical pregnancies this year, and I am childless. Due to my age, I decided to investigate more. The thrombophilia panel test results recommended that I see a hematologist. I have positive results (heterozygous) for MTHFR C677T, PAI 4G by 5G, AGT M235T, factor XIII Val34Leu, and fibrinogen 455 G by A. Will I need special treatment for a future pregnancy?
Please help me.
Thank you.
Hi,
Welcome to icliniq.com.
I have reviewed your case. It seems that you had two miscarriages. So, you have to know a little detail about your condition and understand the thrombophilia panel. The risk of abortion is minimal in normal pregnancy, whereas it is intermediate and high in heterozygous and homozygous mutations, respectively.
In your case, as you have had two pregnancy failures, I have two recommendations. Try to do the APLA test (antiphospholipid antibody workup), which is just an extension of the thrombophilia workup. According to hemato-oncology during future pregnancy, usually in your case, we need to give some medications that can maintain your blood flow, and they can prevent the microclot formation in the placental blood vessels, and hence the chances of abortion will decrease.
These drugs need to be prescribed by your hematologist (low molecular weight Heparin and Warfarin). You can discuss with your hematologist regarding the test suggested and about the drugs that may help you in future pregnancies.
I hope this helps.
Kindly follow up if you have more concerns.
Thank you.
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Answered by Education: DM Hemato-Oncology Professional Bio: Dr.Kamal Kant Sahu is an expert in the field of InternalMedicine. He is experienced and well-versed in all the treatment modalities in Internal Medicine. This doctor is not available for online consultations on the platform anymore. Dr. Kamal Kant Sahu
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Dr. Kamal Kant Sahu
Hematology
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