Which SSRI combination is good for my chronic GAD and SAD?

Question

Hello doctor,

My psychiatrist has decided for years to use only a combination of SSRI and Busipirone permanently to control and manage my chronic GAD and SAD. Which among the SSRIs combination is the best and has the fewest side effects?

Kindly help.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

Coming to SSRI first, the side effects such as sedation and weight gain issues are lower with Prozac (Fluoxetine). While Zoloft (Sertraline) has a lower rate of weight gain and sedation is a little higher compared to Prozac. While Lexapro (Escitalopram) has a little higher incidence of sedation and weight gain.

Sexual dysfunctions are more or less equal to all these drugs. All these SSRIs are quite safe for long-term use. Initially, Prozac can cause some anxiety symptoms. So overall, you can choose from Prozac, Zoloft, and Buspirone, considering your side effects profile.

I hope this helps you.

Thank you.

I hope this has helped you. Thank you.

Answer 2

Hello,

Welcome back to icliniq.com.

Yes, Fluoxetine can also cause weight gain, but the weight gain is less compared to other SSRIs. It is only relative to other SSRIs.

I hope this has helped you.

Thank you.