Thrombosis is the process of formation of hard mass in circulation from the constituents of flowing blood; the mass itself is called a thrombus. When a thrombus develops in an artery, such as in the brain or heart, it is called arterial thrombosis; if it is formed in the veins, it is named venous thrombosis. The occurrence of a thrombus in the deep veins of the leg is known as deep vein thrombosis (DVT).

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What do positive lupus anticoagulants indicate in the first test of antiphospholipid syndrome?

Query: Hi doctor,I have recently been told my first test of antiphospholipid syndrome shows positive lupus anticoagulants. What does that mean for someone with no symptoms? I took Articaine and Phenphedrine the day before the test. Can an overdose cause the test to be faulty? I had four miscarriages so far...  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to You have a history of four recurrent miscarriage and cause for that seems to be an antiphospholipid syndrome. Because of thrombosis secondary to antiphospholipid syndrome, miscarriage occurred. If you are on anticoagulant medication, then it could be a false result. But ...  Read Full »

Even after taking treatment for cerebral venous thrombosis, I still have headaches. Why?

Query: Hello doctor, I was diagnosed with cerebral venous sinus thrombosis, eight months back, after suffering severe headaches. I have never had headaches in my life, except very occasional tensions headaches. I have been taking Warfarin ever since, and I had a follow-up MRI, four months back. The radiolo...  Read Full »

Dr. Hitesh Kumar

Answer: Hello, Welcome to I would like to know some more details about your problem. Since when you started to have headaches? Which part of the head do you have these headaches? Is it same headaches as you had before, or are they different? What kind of headaches are these, heaviness, throbbi...  Read Full »

I feel uncomfortable during sex due to a lump present on my penis. Kindly help.

Query: Hi doctor, I have a small lump inside the foreskin near the penis head. It has been there for more than a year. It is painless. It does not hurt during sexual intercourse but feels uncomfortable during oral sex. Please help.  Read Full »

Dr. Shahil Khant

Answer: Hi, Welcome to I have seen the photos sent by you (attachment removed to protect patient identity). It is dilated vein of the penis. The swelling is because there may be thrombosis (blood clot) inside the vein. Do not worry as it is not harmful at all. It should resolve. I suggest you...  Read Full »

Will thrombophilia cause pregnancy loss?

Query: Hi doctor, My wife is pregnant and has previously had a miscarriage. After her first miscarriage, we did some follow-up blood work. I have attached the reports for your reference. I just wanted a second opinion on them if anything is indicative that this is a high-risk pregnancy and any precautions...  Read Full »

Dr. Sameer Kumar

Answer: Hello, Welcome to Having seen the reports (attachments removed to protect the patient's identity), with ANA (antinuclear antibody) positive status, this makes her a case of inherited thrombophilia where chances of intra-capillary coagulation are increased during pregnancy. The other p...  Read Full »

Will increased D-dimer after COVID infection increase thrombotic complications?

Query: Hi doctor, My husband's D-dimer is 1.2 mg/L on the eleventh day of COVID infection. His CRP level is 0.46 mg. he is 39 years old. His weight is between 95 to 100 kg, and his height is 5'5. Please let me know if there is any test that can predict that thrombosis has stopped working. Is this level of...  Read Full »

Dr. Pawar Satyajit Jalinder

Answer: Hello, Welcome to I would like to know and assess the general condition and health of your husband. Day six to day thirteen of COVID are most important as during these days, the chance of complications is highest. His CRP (C-reactive protein) and D-dimer are well below the alarming ra...  Read Full »

What is therapeutic phlebotomy and why is it done?

Query: Hi doctor, I am an obese person and a non-smoker. I am on an exercise program, and my weight reduced from 132 to 124 kg. I am under therapeutic phlebotomy once in three weeks (before once in two weeks). I found high counts in blood before 14 months during medical fitness blood test abroad and consu...  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to Regular follow-up is my opinion for your question. I have seen the attached reports (attachment removed to protect the patient's identity). Your JAK2 (Janus kinase 2) report is negative, and EPO (erythropoietin) is within the limit. So polycythemia vera, like ...  Read Full »

Will high platelet count cause a blood clot or stroke?

Query: Hello doctor, My mother has high WBC count of 15,000, platelet count of 5,40,000, and hemoglobin at 11.2. Her ESR is 86, and CRP is also similar. She has a fever, which rises in the evening to 101. Can you please tell me what this denotes? Also, will the high platelet count cause a danger for a bl...  Read Full »

Dr. Parth R Goswami

Answer: Hi, Welcome to High platelet count will not lead to thrombosis in the body. Do not worry about that. High platelet is because of reactive thrombocytosis, and that can occur in bleeding, anemia, infection, inflammation, etc. You have an ulcer in the colon, and it seems to be ulcerative...  Read Full »

I have positive cardiolipin IgM and IgG that keeps elevating. Please help.

Query: Hello doctor, I am looking for a third opinion. I have positive cardiolipin IgM and IgG. Tested three times over 11 months. Keeps elevating. What should be done about this? Two current doctors say it is normal.  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to The cardiolipin antibody positive result for two times with 6 to 12-week interval, suggestive of anti-phospholipid antibody syndrome. However, to diagnose the case as antiphospholipid antibody syndrome clinical criteria also should be fulfilled. The clinical criteria...  Read Full »

The veins in arms and legs are bulging with pain. Please help.

Query: Hi doctor, I am 19 years old and I am currently experiencing an issue with the veins in my arms and legs, primarily on the left side of my body. It started about a month ago when I noticed a vein on the top of my left foot that started bulging up out of nowhere. It was concerning but not painful un...  Read Full »

Dr. Ohams Henry

Answer: Hello, Welcome to Your problem looks like varicose vein. Veins will bulge when you are standing or moving around when unlike down it regressed and blood flows back into the deeper veins and empty back into the heart. Varicosity is due to incompetence or weakness in the valves within v...  Read Full »

Will Ashwagandha or Shilajit boost sexual power?

Query: Hello doctor, My age is 19 years old. Recently, I quit smoking and my sexual power is somewhat decreased. How can I boost again my power back? Use of Ashwagandha will help or Shilajit? Or any other advice?  Read Full »

Dr. Parth R Goswami

Answer: Hello, Welcome to You are having erectile dysfunction problem. Smoking, alcohol can lead to that problem. So it should be avoided. For erectile dysfunction rule out vascular narrowing and thrombosis like cause using penile doppler ultrasound. Total cholesterol, blood pressure also sh...  Read Full »

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