Hello,
Welcome back to icliniq.com.
I read your query and understood your concern. Firstly, I would like to inform you that, the challenge with hepatitis B infection is that it has a tendency to persist within the body. The virus can rapidly replicate, leading to an increase in the DNA value. The virus progresses through four stages as mentioned below:
- HbeAg positive and Immunotolerant phase.
- HbeAg Immunoreactive phase.
- HbeAg negative immunotolerant phase (carrier stage).
- HbeAg Immunoactive phase.
You are currently in the HbeAg negative immunoactive phase. Last year, you were in the HbeAg negative Immunotolerant phase. Traditionally, treatment was reserved for immunoactive phases. However, nowadays, antiviral therapies are administered across all four stages due to accumulating evidence and research supporting this approach. It is good that you have decided to initiate Tenofovir Alafenamide 25 mg once daily. You can inquire at your local pharmacy for the available brand in your country of residence. I have also reviewed your reports (attachments removed to protect the patient’s identity), and they appear to be within normal ranges. While your AFP is important, I suggest you undergo the test whenever feasible, as it holds significant importance. Once you have conducted the AFP test, kindly follow up with me. Additionally, another follow-up should occur after three months of taking Tenofovir Alafenamide. This follow-up should include the following tests:
- Alpha-fetoprotein (AFP)
- Complete Blood Count (CBC).
- Serum SGPT: Serum Alanine Aminotransferase (SGPT).
- Serum SGOT: Serum Aspartate Aminotransferase (SGOT).
- HBV DNA quantitative PCR: Hepatitis B Virus DNA quantitative Polymerase Chain Reaction.
I suggest you consult a specialist, talk with them and take the medications with their consent. I hope this has helped you. Kindly follow up if you have more doubts.
Thank you.