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Appendix Cancer - Types, Symptoms, Risk Factors, Diagnosis, Treatment, and Prognosis

Published on Feb 19, 2021   -  4 min read


Appendix cancer is a rare variant of cancer that develops in the appendix. Read this article to know more.


What Is an Appendix?

An appendix is an organ that is found near the intestine. It is situated in the lower right part of the abdomen. Many researchers say that the appendix is an organ that has no useful function or very few functions. Other medical reports suggest that the appendix plays an important role in maintaining the gut health of the individual. In addition to this, it can also contribute to the functioning of the lymphatic system. It is approximately four inches long and attaches to the intestine. There are higher possibilities for the appendix to get infected and result in a condition called appendicitis.

What Is Appendix Cancer?

Cancer is an abnormal and disastrous growth in any part of the healthy tissue. The tremendous growth might decrease the functioning of the cells. When the abnormal cells outweigh the normal cells, it might result in the formation of the tumor or cancer. It can be benign or malignant according to the cells and tissues involved. A type of cancer that originates in the cells of the appendix is known as appendix cancer. It is also known as appendiceal cancer. It is a very rare type of cancer. Less than 100,000 patients have been reported to have appendix cancer in the United States of America.

What Are the Types of Appendix Cancer?

There are different types of appendix cancer:

What Are the Symptoms of Appendix Cancer?

The symptoms of appendix cancer are:

The malignant form of appendix cancer develops on the surface of the spleen, uterus, liver, ovaries, and peritoneum.

What Are the Risk Factors Associated With Appendix Cancer?

The risk factors associated with appendix cancer are:

How Is Appendix Cancer Diagnosed?

Appendix cancer does not produce any symptoms in the initial stages. It might be accidentally revealed during the imaging session of any other conditions like appendicitis. Sometimes doctors identify appendix cancer after the complete removal of the appendix.

Imaging techniques like MRI, CT, and ultrasound procedures can be helpful. Computed tomography is the most preferred scan for most patients. For more precise images, magnetic resonance imaging is recommended by doctors. Blood tests are mostly not helpful for appendix cancer. In some cases, a biopsy is recommended by the doctor where the sample tissue is collected from the involved site and sent for microscopic diagnosis. Most reliable results can be obtained in this technique.

What Are the Treatment Options for Appendix Cancer?

The treatment is planned according to the following criteria:

If the cancer involvement is seen only in the appendix, then minor surgery is sufficient to cure the condition. If cancer has spread to other regions, then surgery is required to remove the cancerous tissue from that site also. This might commonly include ovaries, peritoneum, and intestine.

The American Association of Endocrine Surgeons suggests a hemicolectomy in which the right half of the colon is removed. This method is preferred if the size of the cancer is more than two centimeters.

How Is the Prognosis for Appendix Cancer?

The prognosis for appendix cancer is predicted by the American Society for Clinical Oncology, where the average age is estimated to be around five years. This estimation of five years is grouped according to the following:

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Frequently Asked Questions


Is Appendix Cancer Curable?

We can successfully treat appendix cancer with surgery if it is localized. The surgery includes removing the tumor along with little of the surrounding normal tissues to prevent further spread and recurrence. The survival rate of appendix cancer is 88 percent if it is localized.


How Deadly Is Appendix Cancer?

The appendix is a thin-walled, long, finger-like projection in the right colon. Because of its structure, the tumor can quickly spread in the abdominal cavity and cause serious complications.


Can Anyone Survive Stage 4 Appendix Cancer?

The survival rate of stage 4 appendix cancer is very low because it is a severe condition. The overall survival rate is only 46 percent, and therefore ongoing treatment is required to increase the survival rate.


Who Is at Risk of Appendix Cancer?

The people who are at risk for appendix cancer are:
- Smokers.
- Patients with a family history of appendix cancer or multiple endocrine neoplasia type 1 (MEN1) syndrome, also known as Wermer syndrome or endocrine adenomatosis, have a higher risk for appendix cancer.


Can Colonoscopy Be Used to Detect Appendix Cancer?

Appendix cancer is sporadic because its causes and prevention are still not known. Since it is very hard to detect, it can be accidentally detected while doing a preventive colonoscopy for colon cancer.


Where Can Appendix Cancer Spread To?

Appendix cancer can be localized, but can also spread outside the appendix to the colon, rectum, small intestine, and stomach. It is regional when it spreads to the nearby lymph nodes and tissues, and metastatic when it spreads to other parts of the body.


How Prevalent Is Appendix Cancer?

Most cases of appendix cancer occur after the surgery for acute appendicitis. It can happen at any age and is most commonly seen in the sixth decade of life.


How Does Appendix Cancer Begin?

Appendix cancer begins when the DNA in the appendix's cells gets mutated and grows rapidly. This appendix tumor or growth will break through the appendix and form a mucin-like fluid that will flow into the abdominal cavity and stop the functions of the digestive organs like the small bowel, colon, and liver.


How Do You Feel If You Have Appendix Cancer?

Appendix cancer does not cause any symptoms, but the most common symptoms are a larger belly and bloating. The less common symptoms are fever, nausea, vomiting, hard stools, or diarrhea.


Can Cancer from the Appendix Spread to the Lungs?

The appendix usually forms a small amount of mucus; therefore, these tumors in the appendix may form a large amount of mucin-like thick fluid in the belly, which may spread to the lungs, liver, and lymph nodes.

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19 Feb 2021  -  4 min read




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