HomeHealth articlesvitamin cVitamin C Toxicity | Symptoms | Uses | Side Effects | Precautions

Vitamin C Toxicity - Symptoms, Uses, Side Effects and Precautions

Verified dataVerified data
16

3 min read

Share

Intake of vitamin C, a water-soluble vitamin, is necessary for the body's functions. At higher intakes, vitamin C does not cause serious effects.

Medically reviewed by

Dr. C. Elanchezhian

Published At March 16, 2022
Reviewed AtNovember 14, 2023

What Are the Uses of Vitamin C?

Vitamin C is also known as ascorbic acid. Vitamin C plays a pivotal role in many body functions such as;

1.Helps in the absorption of iron.

2.Helps in the formation of amino acids, hormones, and collagen.

3.It supports wound healing.

4.It is essential for bone and blood vessel health.

5.It is an antioxidant.

6.It supports the immune system.

Due to all these functions of vitamin C, dietary intake of vitamin C is essential as the body does not produce or store vitamin C. The primary sources of vitamin C are citrus fruits, broccoli, strawberries, potatoes, and tomatoes. For adults, 75 to 90 mg is the daily recommended dose. The maximum limit is 2000 mg per day. If the intake of vitamin C exceeds the maximum limit, it can cause nausea, diarrhea, vomiting, etc. Such a condition is known as vitamin C toxicity.

What Are the Symptoms of Vitamin C Toxicity?

When the intake of vitamin C exceeds the maximum limit that is 2000 mg/day, it can cause,

  1. Diarrhea

  2. Nausea and vomiting.

  3. Abdominal cramps.

  4. Insomnia.

  5. Headache.

  6. Fatigue.

  7. Heartburns.

  8. Fever.

  9. In some cases, vitamin C is taken in higher doses; for example, for reversing cancer progression, the recommended dosage is 10 g/day in such cases. Such doses can acidify urine, leading to the formation of kidney stones. It may affect the body's antioxidant–prooxidant balance, leading to oxidative stress that can cause cell and tissue damage.

In patients with blood disorders like thalassemia, it can cause iron overload (too much iron in the body).Vitc

The recommended dosage of vitamin C varies among different age groups.

Dosage of Vitamin C

In pregnancy and lactation, the recommended dosage is more. During pregnancy, the recommended dosage is 80 to 85 mg/day and during lactation recommended dosage is 115 to 120 mg/day.

For the infants, the requirement should be met through diet, and individuals who smoke may require 35 mg more of vitamin C than non-smokers daily.

What Are the Severe Side Effects of Vitamin C Toxicity?

Some of the severe side effects of vitamin C toxicity include kidney stones, bone spurs (bony projections that develop along the bone edges), and nutrient imbalance. Excessive vitamin C can also affect the action of the drug Niacin-Simvastatin.

  • Kidney Stones – When there is an excess of vitamin C, it may result in the formation of oxalates and uric acid in the urine leading to kidney stones.

  • Bone Spurs – According to studies the excess vitamin C can be a cause for bone spurs. But when the levels of vitamin C are low, studies say that it can also cause rheumatoid arthritis. So there should be an appropriate supplementation of vitamin C.

  • Nutrient Imbalances – When there is excess vitamin C in the body, it can interfere with the absorption and levels of other nutrients. Excess vitamin C can enhance iron absorption, which is very dangerous in individuals suffering from blood disorders like hemochromatosis. It may also reduce vitamin B-12 absorption.

  • Action on Niacin-Simvastatin– Taking excess vitamin C may affect the body’s ability to produce high-density lipoprotein (HDL) in patients taking the Niacin-Simvastatin combination.

When to See a Doctor?

If you observe any symptoms like diarrhea, vomiting, nausea, or any other symptoms mentioned above after taking vitamin C supplementations, consult a doctor immediately.

What to Do in Case of Vitamin C Toxicity?

In case of vitamin C toxicity, immediately stop the consumption of vitamin C supplements. Drink lots of water so that excess amounts of vitamin C can be flushed out. Consult your physician immediately if you are on any other medications like Niacin or chemotherapy. For the symptoms like vomiting and nausea, over-the-counter drugs can be taken.

Conclusion:

Vitamin C is essential for the proper functioning of our body. But when taken in excess, it may cause adverse symptoms. In a healthy individual, vitamin C toxicity can be easily managed. There is no chance that you will die from vitamin C toxicity if you are healthy. However, if you are on any other medications, it is always best to seek medical help in case of vitamin C toxicity.

Frequently Asked Questions

1.

What Is the Recommended Dose of Vitamin C per Day?

The recommended dose of vitamin C daily is 65 to 90 milligrams (mg), and the maximum recommended dose is 2,000 mg daily for adults.

2.

Is Vitamin C Toxicity Common?

Vitamin C is a water-soluble vitamin. Hence, the chance of vitamin C toxicity is very low. However, large vitamin C consumption may cause diarrhea, nausea, or vomiting.

3.

How Do You Treat Vitamin C Toxicity?

Vitamin C is a water-soluble vitamin, unlike fat-soluble vitamins. So if someone consumes an excess amount of vitamin C and develops diarrhea, nausea, or vomiting, they should drink plenty of water, which will help them flush out the excess of vitamin C. They should consult a doctor about chemotherapy or other medicines like Niacin. They can also take over-the-counter drugs for vomiting or diarrhea.

4.

Can Vitamin C Cause Kidney Stones?

The intake of vitamin C also called ascorbic acid, is a risk factor for kidney stones. Vitamin C increases urinary oxalate excretion, a type of calcium salt responsible for stones.

5.

Does Vitamin C Has Any Side Effects?

Taking an excessive amount of vitamin C can cause side effects, like:
- Nausea and vomiting.
- Diarrhea.
- Heartburn.
- Stomach ache or bloating.
- Fatigue and sleepiness.
- Insomnia in some people.
- Headache.
- Skin flushing.

6.

Does Vitamin C Have Any Link With Sleep?

Vitamin C plays an important role in improving sleep health. Studies have shown that individuals with greater concentrations of vitamin C in their bodies have a better night's sleep than those with reduced concentrations.

7.

Which Is the Most Likely Vitamin to Cause Toxicity?

The vitamins that are not water soluble are the ones that cause vitamin toxicity. These fat-soluble vitamins include vitamins D, E, A (retinol), and K. Among them, vitamins D and A are the most toxic and can cause toxicity.

8.

Who Should Not Take Vitamin C?

People with an inherited condition with too much iron buildup called hemochromatosis. As they are water soluble they are generally safe for consumption by anyone. However, consuming over 2000 mg of vitamin C daily may cause diarrhea, gas, or stomach upset.

9.

What Effect Does Vitamin C Have on the Skin?

Vitamin C can benefit the skin in many ways. It will help delay aging signs, prevent sun damage, and improve wrinkles and dark circles under the eyes. But when the vitamin C in the form of serum is acidic, it may cause skin irritation in some people.
Dr. C. Elanchezhian
Dr. C. Elanchezhian

General Medicine

Tags:

vitamin c
Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Source Article ArrowMost popular articles

Do you have a question on

vitamin c

Ask a doctor online

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy