Q. I get abdominal distension and persistent diarrhea with high ALT and AST values. What is my problem?

Answered by
Dr. Hiren Patel
and medically reviewed by Dr. Vinodhini. J
This is a premium question & answer published on Jun 06, 2020

Hi doctor,

I am 49 years old and I have been drinking approximately 350 ml of vodka every day for approximately 10-15 years. I also have smoked half pack a day for 30 years but just recently quit. For the past year and a half (maybe even two years) I have had diarrhea daily. I went to a doctor who prescribed IBS medicine and B12 shots, but nothing changed. My stomach is large, distended, and hard. When I eat half a sandwich or six bites of salad, I am so bloated I cannot move. I feel a dull bruise like pain (very dull) in my lower right quadrant from time to time maybe once every two weeks.

My AST and ALT levels are high (112 and 113), glucose is 116, absolute eosinophils are 720H. I have attached my lab reports. My guess is, this is liver disease, pancreas disease, or diabetes. Any ideas? Do I have to quit drinking? Or can I cut back?

I am currently taking Stelara for psoriasis.



Welcome to

I think there are multiple issues. You need proper workup. Your ALT (alanine transaminase) / AST (aspartate transaminase) are due to alcohol-related liver disease, better is to do USG (ultrasound) abdomen.

Other issues are, I had gone through your blood reports (attachment removed to protect patient identity). Your hemoglobin and hematocrit are in range of polycythemia vera which is a blood coagulation disorder. So what is feel is you need a good doctor hematologist for polycythemia and related to your gastric issues.

USG abdomen and endoscopy with biopsy can be done if possible, as this will tell us liver and pancreas status as alcohol affects both. Second thing, stop smoking which is a culprit for your high Hb so to get that worked up there are series of tests need to be done. My advice is to choose a good doctor to get everything thing done.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
My husband has not had a bowel movement in two days. Why?

.. complaints are constipation, giddiness on standing and discoloration of urine. Let me explain each. In diabetes, constipation could be due to diabetic gastropathy, in which the movement of the intestine is slow. It does not, however, happen sudden...   Read full

Antibiotic-Associated Diarrhea (AAD)

.. the passing of watery stools after taking antibiotics. It results from infection by antibiotic-resistant pathogens .. ...   Read full

My asthmatic mother's X-ray is negative for TB. What else this could be?

.. checked the attached report, along with the data you provided (attachment removed to protect patient identity). Your mother has COPD which is a chronic obstructive lung disease due to changes in the lung with age and due to smoking. In COPD the ai...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

Sexual Problems and Depression
Depression is one of the commonest psychiatric problems in the general population. About 10 % of men and more than doubl...  Read more»
Holiday Season During the Pandemic
Most of us wonder if there is a way to celebrate the holiday season during the COVID-19 pandemic safely. Here are some i...  Read more»
Skin Care Tips To Win Over Winter
This article discusses a few tips to manage and protect your skin during winter.  Read more»

Ask your health query to a doctor online?

Ask a Medical Gastroenterologist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.