What are the possible causes for declining blood tests results and an elevation in BP?

Hi,

Welcome to icliniq.com.

I read your query and understand your concern.

I have reviewed all your reports (attachments removed to protect the patient's identity), ultrasound findings, and medical history. The lab report indicates elevated liver enzymes, including SGOT (serum glutamic oxaloacetic transaminase), SGPT (serum glutamic pyruvic transaminase), and LDH (Lactate dehydrogenase).

I will discuss each one separately. Both SGOT and SGPT indicate hepatitis (liver inflammation), but typically, the enzymes should rise at least five times their normal values. SGOT does not quite fit this pattern, but SGPT is significantly elevated. LDH suggests hepatocyte destruction (damage or death of hepatocytes) in the liver. The correlation with elevated ferritin levels, increased transferrin saturation, and high ferritin levels is of utmost importance. A high ferritin level suggests an abundant iron deposition in liver cells, leading to the destruction of liver cells. Given these findings, I suggest undergoing liver elastography, a highly specific test, a non-invasive imaging technique used to measure the stiffness of liver tissue. The potential reasons behind these abnormalities could be autoimmune issues, alcohol consumption, drug-induced effects, or parenteral iron intake.

Please provide more information by answering the following questions:

1. Do you have any history of drug intake, excluding Candesartan?

2. Is there any history of alcohol consumption?

3. Are there any relevant family medical histories?

Kindly revert to assist you further.

Please feel free to ask if you have any further questions.

Thank you.

Hello,

Welcome back to icliniq.com.

I read your query and can understand your concern.

Liver elastography (a non-invasive imaging technique used to measure the stiffness of liver tissue) will provide clarity on many aspects. The increased iron load in your body, stored in the liver, is likely responsible for your symptoms. I suggest discontinuing all iron supplements, red meat, and processed foods. Once the elastography report is available, please inform me. I will then guide you on the next steps. If the iron load is indeed elevated, we can initiate iron detoxification therapy.

I hope this helps.

Please revert in case of further queries.

Thank you.

Hello,

Welcome back to icliniq.com.

I read your query and can understand your concern.

I have reviewed your reports (attachments removed to protect the patient's identity), and it is a positive sign that the liver maintains its normal size with no significant hepatocyte (cell of the liver) injury. However, there are indications of fatty liver changes which align with your clinical symptoms.

I suggest the following treatment plan. Kindly consult your doctor and take the medicines:

1. Aim to reduce your weight by 8.8 to 11 pounds.

2. Undergo a lipid profile test to assess cholesterol or fat levels.

3. Recheck serum ferritin levels after three months.

4. I suggest taking the tablet Udiliv 150 mg (Ursodeoxycholic acid or Ursodiol 150 mg) twice daily for two weeks, then once daily for the next two weeks.

   I hope this helps.

   Please revert in case of further queries.

   Thank you.