Common "Bone Marrow Aspiration" queries answered by top doctors | iCliniq

Bone Marrow Aspiration

The procedure done to collect a sample of the bone marrow, which is the soft tissue core of large bones, is called bone marrow aspiration. The sample is collected by inserting a hollow needle through the skin and into the bone. This procedure is done to diagnose conditions like anemia, blood cancer, hemochromatosis, infections like tuberculosis, and other bone marrow diseases.

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Why does bone marrow aspiration and biopsy report differ?

Query: Hi doctor, Bone marrow aspiration twice showed hypercellular bone marrow with overgrowth of WBC and megakaryocytes with all stages of maturing including micro-megakaryocytes. But at the same time, the second BMA during bone marrow biopsy showed normocellular bone marrow. Is something like that possi...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to You have not mentioned the age of the patient, peripheral smear, and CBC (complete blood count) findings. You mentioned that bone marrow was showing overgrowth of the WBC (white blood cells) and micro megakaryocytes. So, it is a myeloproliferative condition. Here, cli...  Read Full »

My friend is diagnosed with stage 4 leukemia. Please help.

Query: Hi doctor, Can you help me read the attached report of my friend's blood test? Please explain about her condition. I want to check if the patient is diagnosed with leukemia.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to Here, in the attached report (attachment removed to protect patient identity), some part of the peripheral smear examination report is not visible in leukocyte. Upload the peripheral smear examination report, which is fully visible, so that I can comment on it. The le...  Read Full »

What is the treatment for acute lymphoblastic leukemia?

Query: Hello doctor, A 39-year-old female patient is suffering from acute lymphoblastic leukemia. She is currently being treated at a hospital by an oncologist. I am attaching her reports. Please suggest a treatment.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to I am sorry to hear about the patient's condition. I have gone through the reports (attachment removed to protect patient identity). Lymphoblast is an abnormal form and in leukemia, premature cells are seen in the blood in increased number. So, as the blast cells wer...  Read Full »

My son has neutropenia. Is it caused by DPT vaccine?

Query: Hi doctor, My son is 15 years old. He got his DTaP vaccine two weeks ago and had CBC 20 days later. All came well except neutrophil count, which came back as 800, and total WBC as 2500. We are going to repeat the test tomorrow. Can the vaccine be the cause of the neutropenia? And if so, how long wil...  Read Full »

Dr. Prakash. H. M.

Answer: Hi, Welcome to Based on your query, my opinion is as follows: I doubt the vaccine could be the cause of neutropenia (neutrophil count less than normal). Though it can take place in some cases like the Influenza virus vaccine, DTP (diphtheria, tetanus, and pertussis) have not been ...  Read Full »

How to manage microcytic hypochromic anemia with thrombocytopenia?

Query: Hi doctor,My partner was admitted to the hospital for a low platelet count, and she was asymptomatic. They did a blood transfusion and gave corticosteroids. There was no improvement in her platelet level. The doctor suggested me to consult a hematologist. On her recent reports, her platelet count wa...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to I have gone through the attachment (attachment removed to protect patient identity). Her platelet count is low in the manual as well as on the cell counter. So infective etiology has to be ruled out first. If there is no sign of any infection, then ultrasonography abdom...  Read Full »

My Hb is around 12. Should I seek bone marrow aspiration?

Query: Hello doctor, I am a 25-year-old man without major systemic diseases before. I am actually a medical student now. During the general examination this year, I noticed my Hb level around 12 to 13 g/dL. Follow up data in the following months showed 12.7 > 12.8 > 12.4 > 12.6. Normocytic (84), b...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to You are a medical student, so obviously you are very much alert about health. I have reviewed your query and here is my advise. Your CBC (complete blood count) report is not showing any abnormality except borderline hemoglobin level. You are right in that the male h...  Read Full »

I have idiopathic thrombocytopenic purpura. Can I get pregnant?

Query: Hello doctor,I am a 26-year-old girl who suffered from idiopathic thrombocytopenic purpura, three months ago. I was under treatment for the next three months with Corticosteroids and Imuran (Azathioprine). After three months doctor did not give me any treatment as my platelet count was normal. Now I...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to I went through your query and understood your concern. The cause for your reduced platelet count was not clear. If no cause is found then it could be idiopathic thrombocytopenic purpura (ITP). A bone marrow aspiration study can be done to confirm it. This disease sho...  Read Full »

Is there any correlation between fluctuating BP and increasing WBC count?

Query: Hi doctor,Can fluctuate blood pressure cause elevated WBC? I got sick with chronic idiopathic urticaria and started MTX. My Rheumatologist diagnosed me with seronegative RA and stopped MTX. Did Vectra DA test, and scored 42/moderate for RA disease. I was supposed to start Remicade this Thursday, but...  Read Full »

Dr. Nagaraj

Answer: Hi, Welcome to Thank you for providing a detailed history. To answer your first query, there is no direct correlation between fluctuating BP and the increase in cell counts. CRP is usually elevated in RA (rheumatoid arthritis) disease, which is a common finding reflecting the body's ...  Read Full »

Bone marrow aspiration cytology shows 11 % blast cells. What has to be done?

Query: Hello doctor,Bone marrow aspiration cytology was done for my father who is 77 years old and the report shows the presence of 11 percent of blast cells (about two months ago). Kindly advise the next line of management. His ninth chemotherapy was completed three months back. Now laboratory report is s...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to You have not achieved complete remission from chemotherapy. Usually, complete remission can be considered only when blast cells in bone marrow are less than 5 % and platelet count more than one lakh. So, you can go for combination chemotherapy to achieve that target....  Read Full »

How to treat multiple myeloma at home?

Query: Hello doctor, My father is 54 years old. His weight is 136 lbs, and his height is 5.5 feet. He was hospitalized last year because of lower back pain after sneezing. He was diagnosed to have lumbar strain versus HNP. He was again hospitalized three months back and was diagnosed with compression fract...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to In the attached report (attachment removed to protect the patient's identity), there is a spike in the gamma region. Monoclonal immunoglobulin has increased. So it seems to be multiple myeloma. His creatinine and calcium are also increased. So treatment needs to be...  Read Full »

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