Get E-Book on COVID-19

Q. Can fluctuating blood pressure cause elevated WBC?

Answered by
Dr. Nagaraj Patil
and medically reviewed by Dr. Hemalatha
This is a premium question & answer published on Jan 08, 2020

Hi doctor,

Can fluctuate blood pressure cause elevated WBC? I got sick with chronic idiopathic urticaria and started MTX. My Rheumatologist diagnosed me with seronegative RA and stopped MTX. Did Vectra DA test, and scored 42/moderate for RA disease. I was supposed to start Remicade this Thursday, but my blood pressure started fluctuating as high as 189/108 mmHg to 138/83 mmHg with low HR as low as 43 at rest. In ER, they checked heart, lungs, and kidneys. They referred me to a Cardiologist, and she added a new medicine Edarbi 40 mg, but said WBC is 20.11, with polys 93.1 and lymph 3.5.

I was referred to a Hematologist. He said that it looks to be some bone marrow abnormalities and suggested more extensive blood tests to see if reactive effect to inflammation or blood disease or cancer. The other symptoms are weakness, fatigue, and intermittent slight shortness of breath, but I suspected all was due to pressure or heart rate issue. Fever, chills and body ache lasted for one day. I was fine after I took 500 mg Naproxen. There is no cold symptom with fever. I saw my Rheumatologist, and she said it is not RA related based on high polys. CRP ranged from 7.2 to 17.6 earlier that is before two years, and now almost at its lowest at 8. Does this look like a body reacting to inflammation or pressure or heart rate? Also, I have intermittent pain in lower left abdominal area. I do not see my Hematologist for follow up until next month and cannot start Remicade until I get it figured out.

Dr. Nagaraj Patil

General Medicine Internal Medicine


Welcome to

Thank you for providing a detailed history.

To answer your first query, there is no direct correlation between fluctuating BP and the increase in cell counts.

CRP is usually elevated in RA (rheumatoid arthritis) disease, which is a common finding reflecting the body's reaction to inflammatory or autoimmune disorders like RA.

Though your BP is now controlled to some extent, the low pulse rate could be because of Bystolic 5 mg (Nebivolol). You need a review with your Cardiologist for the same.

Also, looking at your non-specific symptoms like weakness, fatigue, intermittent shortness of breath, fever, chills along with elevated differential white cell counts, it is advisable to have bone marrow examination done to rule out hematological malignancy.

I am not convinced with your RR of 98. Have you checked it correctly? Please update. Thank you.

Investigations to be done:

Bone marrow aspiration.

Regarding follow up:

Review with Cardiologist and Hematologist.

Was this answer helpful?


Related Questions:
Blood pressure seems unusually high in 4 year old. Is there a problem?
High Blood Pressure: Things You Need To Know!!
Why is my neutrophil number dropping?

This is a sponsored Ad. icliniq or icliniq doctors do not endorse the content in the Ad.

Consult by PhoneConsult by Phone Video ChatVideo Chat
Also Read Answers From:

Comprehensive Medical Second Opinion.Submit your Case

Related Questions & Answers

Kindly clarify the results of my CBC report.

Query: Hi doctor, I am a 38-year-old male. I have a question about my CBC report. My lymphocytes are high with 65 %. My neutrophil levels are low. My total WBC is 3200 WBC per microliter of blood. I have these levels remaining the same for about two years. I have constant body pain. I am very weak, and I ...  Read Full »

My baby's WBC count is high two months after an infection. Is it cancer?

Query: Hi doctor, My son turned one two months ago. He was last sick two months ago for about a week. He had some standard vaccinations and a routine CBC to check for lead level and anemia. The CBC came back with high WBC and high platelets. His pediatrician was not concerned and said it could be from a re...  Read Full »

Bone marrow aspiration cytology shows 11 % blast cells. What has to be done?

Query: Hello doctor, Bone marrow aspiration cytology was done for my father who is 77 years old and the report shows the presence of 11 percent of blast cells (about two months ago). Kindly advice the next line of management. His ninth chemotherapy was completed three months back. Now lab report is showin...  Read Full »

Also Read

Crohn's Disease
Crohn's disease causes inflammation of the digestive tract, which results in symptoms like severe diarrhea, stomach pain...  Read more»
I was diagnosed with Celiac disease a year back. Can you suggest any medicine?
Having celiac fromnlast 10 year dignosis recently ayear ago since then i am gluten free still cant absorb food feeling w...  Read more»
My head is shivering from 20 days, and it feels like head trauma. What is the cause?
Hello sir, My head is shivering like anything , feeling like trauma is head. And its start anytime in a day and when s...  Read more»

Ask your health query to a doctor online?

Ask a General Medicine Physician Now

* guaranteed answer within 4 hours.

Disclaimer: All health Q&As published on this website is not intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek the advice from your physician or other qualified health-care providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.