Is it possible for a BRCA1 mutation lead to breast cancer?

Question

Hi doctor,

I am 30 years old. I have a BRCA1 genetic mutation that is still undergoing more research, as they are not sure of the exact risk yet. My mom had breast cancer at the age of 56, and her cousin had the same at the age of 46. They were both positive to hormonal therapy. Another cousin had ovarian cancer at the age of 49. They are all cancer-free now.

I have a fibrocystic breast and one fibroadenoma confirmed with a biopsy three years ago. I had an ultrasound scan three months ago and found more cysts and nothing major to worry about. I had another ultrasound a week ago as I felt a new little lump.

That lump turned out to be another cyst, but the doctor found another lump she had not seen three months before. It has regular borders and it is movable, but it has some vascularities. She says it cannot be a cyst and could be a fibroadenoma, but it has to be confirmed by a biopsy, which I will have next week.

I know that sometimes triple-negative breast cancer lumps can be mistaken for fibroadenoma, but how likely is that chance? I am feeling quite anxious and worried. With a fibrocystic breast, is it possible to have a fibroadenoma appear this fast? Or is it possible that an ultrasound would have missed it last time?

Kindly suggest.

Thank you.

Answer 1

Hi,

Welcome to icliniq.com.

Since you have BRCA1 (breast cancer type 1) positive with a strong family history of breast cancer, there is always a risk of developing cancer. You need to have a regular follow-up.

Ultrasound may miss early changes. Since you have a high tendency to develop cancer, you can undergo a complete mastectomy. It is a tough decision for you, but it is worth it.

I hope this information will help you.

Kindly follow up if you have more concerns.

Thank you.

Answer 2

Hi,

Welcome back to icliniq.com.

It seems benign, but you should be alert and not delay any treatment or routine follow-up with your doctor. I am always there to help.

Feel free to reach out in case of any further queries.

Thank you.