HomeAnswersObstetrics and GynecologyceaMy 56-year-old aunt has a high CA-125 value. Please help.

What could be the reason for the high CA-125 and CEA value in a 56-year-old woman?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At October 6, 2022
Reviewed AtOctober 10, 2023

Patient's Query

Hello doctor,

My aunt is 56 years old. She has 24 to 25 mm endometrial thickness with internal vascularity. Her CA-125 value is 50.1 units/L, and her CEA is 6.4 µg/L. I think she has reached menopause because her FSH is high (91 IU/L), and she has post-menopausal bleeding. During a physical examination, a solid mass was felt beneath the vagina. She also has low hemoglobin, and her pap smear test is negative. What is the most likely cause? And what is the best course of treatment and diagnosis? Because she also has other co-morbidities like epilepsy, blood pressure, and varicose veins. Currently, she is on Metoprolol, Tegretol, and Folic acid.

Answered by Dr. Richa Agarwal

Hello,

Welcome to icliniq.com.

I have gone through your history and understand your concerns. Your aunt's symptoms are suggestive of hormonal imbalance due to her age, or it can be due to the menopausal stage. You must go for laparoscopic hysteroscopy dilation and curettage and send tissue for biopsy to rule out carcinoma.

There is a possibility that polyps or mass should be ruled out with the help of an MRI (magnetic resonance imaging) pelvis.

Regards.

Patient's Query

Hello doctor,

Since hysteroscopy is invasive, is MRI pelvis reliable to identify the cause if it is a polyp or hormonal imbalance, or carcinoma? Will the results be conclusive?

Answered by Dr. Richa Agarwal

Hello,

Welcome back to icliniq.com.

MRI (magnetic resonance imaging) pelvis can help to rule out if there is mass, but for hormonal imbalance, hysteroscopy and biopsy are recommended.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Richa Agarwal
Dr. Richa Agarwal

Obstetrics and Gynecology

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