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What could be the reason for the high CA-125 and CEA value in a 56-year-old woman?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My aunt is 56 years old. She has 24 to 25 mm endometrial thickness with internal vascularity. Her CA-125 value is 50.1 units/L, and her CEA is 6.4 µg/L. I think she has reached menopause because her FSH is high (91 IU/L), and she has post-menopausal bleeding. During a physical examination, a solid mass was felt beneath the vagina. She also has low hemoglobin, and her pap smear test is negative. What is the most likely cause? And what is the best course of treatment and diagnosis? Because she also has other co-morbidities like epilepsy, blood pressure, and varicose veins. Currently, she is on Metoprolol, Tegretol, and Folic acid.

Answered by Dr. Richa Agarwal

Education:

MBBS

Professional Bio:

Dr. Richa Agarwal is an Obstetrician and Gynecologist with 26 years of clinical experience. She completed her MBBS and DGO at the Rani Durgavati Vishwavidyalaya. She treats health issues in women during and after pregnancy and is concerned with the fetus's health. Currently, she is practicing in Gurgaon, Haryana, India.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I have gone through your history and understand your concerns. Your aunt's symptoms are suggestive of hormonal imbalance due to her age, or it can be due to the menopausal stage. You must go for laparoscopic hysteroscopy dilation and curettage and send tissue for biopsy to rule out carcinoma.

There is a possibility that polyps or mass should be ruled out with the help of an MRI (magnetic resonance imaging) pelvis.

Regards.

Patient's Query

Hello doctor,

Since hysteroscopy is invasive, is MRI pelvis reliable to identify the cause if it is a polyp or hormonal imbalance, or carcinoma? Will the results be conclusive?

Answered by Dr. Richa Agarwal

Education:

MBBS

Professional Bio:

Dr. Richa Agarwal is an Obstetrician and Gynecologist with 26 years of clinical experience. She completed her MBBS and DGO at the Rani Durgavati Vishwavidyalaya. She treats health issues in women during and after pregnancy and is concerned with the fetus's health. Currently, she is practicing in Gurgaon, Haryana, India.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome back to icliniq.com.

MRI (magnetic resonance imaging) pelvis can help to rule out if there is mass, but for hormonal imbalance, hysteroscopy and biopsy are recommended.

Medically reviewed by iCliniq medical review team
Published At October 6, 2022
Reviewed At October 10, 2023

Education:

MBBS

Professional Bio:

Dr. Richa Agarwal is an Obstetrician and Gynecologist with 26 years of clinical experience. She completed her MBBS and DGO at the Rani Durgavati Vishwavidyalaya. She treats health issues in women during and after pregnancy and is concerned with the fetus's health. Currently, she is practicing in Gurgaon, Haryana, India.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Richa Agarwal is an Obstetrician and Gynecologist with 26 years of clinical experience. She completed her MBBS and DGO at the Rani Durgavati Vishwavidyalaya. She treats health issues in women during and after pregnancy and is concerned with the fetus's health. Currently, she is practicing in Gurgaon, Haryana, India.

This doctor is not available for online consultations on the platform anymore.

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