Dr. Utkarsh Sharma
Pathology
The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.
Answered by
Medically reviewed by
Patient's Query
Hello doctor,
I have been getting a fever every other night or once a month during the night. I have also been getting sick with body aches and fevers with diarrhea. The labroratory ran a complete blood test, and on the SPEP test, they noticed a spike in the gamma region. They performed an immunofixation electrophoresis, and a comment mentions biclonal IgG Kappa. I wanted clarification on what it means. My doctor said he would call me regardless of the results, but I haven’t heard back yet.
Hello,
Welcome to icliniq.com.
I understand your concern. Biclonal gammopathy involves the presence of 2 or more M-proteins in serum or urine. It may occur due to the production of monoclonal immunoglobulins from two plasma cell clones or two monoclonal proteins from a single plasma cell clone. Monoclonal gammopathy of undetermined significance is (MGUS) is a precursor of multiple myeloma and is present in 3 to 4 percent of the population above 50 years of age. Of this population, 5 to 6 percent have biclonal gammopathy, which has a better prognosis. For further evaluation, you should get a complete blood count, which will reveal your Hb (hemoglobin) levels that might be low causing body ache and tiredness. A radiological examination to find any plasma cell-associated bone lesions and a kidney function test are also required. A bone marrow aspirate and biopsy might be necessary if clinically indicated.
Was this conversation helpful?
Same symptoms don't mean you have the same problem. Consult a doctor now!
Pathology
Related Questions
What causes body pain during pregnancy?
I just got HIV-1 and HIV-2 tests done. Can you help me understand the report?
I have severe fever and body pain but I have taste and smell sensation. Please help.
I have body pain and loose stools even after taking medication for vitamin D deficiency. Why?
After the first chemotherapy session for CLL, my dad has a persistent fever. Why?
Having on and off pain around pelvis and femur junction. What could it be?
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.
This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy
