I am 21 years old. I have a problem of premature ejaculation. I have read 30 mg Dapox is effective for treatment of premature ejaculation. Can I start with od dose of Dapox? And for how long should I continue the medicine? Are there any long term side effects of Dapox? Can I take Duralast? I am taking Minoxidil for hair loss. Please guide.
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Dapoxetine belongs to the fast-acting selective serotonin reuptake inhibitor (SSRI) group of drugs and was originally created as an antidepressant. As they get absorbed and eliminated from the body rapidly, they are not suitable for the treatment of depression and other psychiatric illness. Presently, it is being used in the management of premature ejaculation (PE), but it is not FDA-approved. Multiple trials have confirmed the efficacy of different doses of Dapoxetine on managing different types of PE
The exact mechanism of action is not known, but Dapoxetine is believed to increase the activity of serotonin, which is a neurotransmitter that passes signals between nerve cells, in the central nervous system. This somehow increases the time it takes to ejaculate and improves control over the ejaculation.
Men aged 18 to 64 years can take Dapoxetine if they are suffering from premature ejaculation. Some of the indications for this medicine are:
Men with intravaginal ejaculatory latency time (IELT) less than 1 minute. IELT is the time taken to ejaculate during vaginal sex.
Repeated PE with minimal sexual stimulation.
Relationship problems due to PE.
Men who ejaculated prematurely, the majority of the time over the past 6 months.
No or poor control over ejaculation.
No, Dapoxetine is not for continuous daily use. Dapoxetine is available in 30 and 60 mg doses. All patients are started with 30 mg, which needs to be taken 1 to 3 hours before anticipated sexual activity. It should not be taken more than once in 24 hours.
If your doctor feels that 30 mg is not sufficient, and if it did not cause any adverse effects, then the dose might be increased to 60 mg.
It is relatively safe and effective to use Dapoxetine. As it is a fast-acting SSRI, it is rapidly absorbed and excreted from the body in a few hours. This results in minimal drug getting accumulated in the body, which leads to no or fewer side effects.
The common side effects seen are nausea, dizziness, dry mouth, diarrhea, insomnia, and headache. And rarely, it causes decreased libido and erectile dysfunction.
For a single dose of 30 mg and 60 mg, Dapoxetine is eliminated in the urine after 18 and 21 hours respectively. It reaches maximum plasma concentration after 1 to 2 hours of oral administration.
Premature ejaculation cannot be cured but can only be controlled. Dapoxetine helps in delaying and controlling ejaculation only when taken 1 to 3 hours before sex.
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