Is my extremely dry mouth due to the Botox treatment which I took two months ago?

Q. Can Botox treatment lead to extremely dry mouth?

Answered by
Dr. Kuljyot Bajaj
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on May 08, 2022 and last reviewed on: Sep 07, 2023

Hello doctor,

I have an extremely dry mouth with no saliva at all. I have been seeing a rheumatologist because I thought the dry mouth was from Sjogren, and so did they. But I just got a lip biopsy which said it is not due to Sjogren. The only thing I can think of is that this all happened about one month after a botox treatment for masseter muscles to alleviate teeth grinding. I think they could have accidentally injected the parotid glands or the submandibular nerve, as it is about one cm away from the masseter muscles. But it has been almost two months since that treatment now. Currently, I am taking Duloxetine, Xanax, Ambien, and Evoxac.



Welcome to

Thank you for your query. May I please ask you a bit more about your symptoms? Has this been the first episode of dryness? If you think it is related to Botox injection, then how many days following injection did you start feeling dry mouth? What was the reason for injection in that area? Do you have any other underlying medical conditions?


Hello doctor,

Thank you for the reply.

This is my very first episode of dry mouth. About 30 days after the Botox injection, I started having symptoms, and they progressively got worse in another 30 days. I had teeth grinding, and this Botox injection was to minimize that. I have no other underlying medical conditions.



Welcome back to

Dry mouth is one of the rare side effects that one can have following the Botox injection, but it is transient and gets better in a few days. Very rarely, it can persist for a few months. The persistence of this side effect has been reported in very few cohorts of patients in the literature. At this point, I would suggest drinking lots of fluids and soft foods like yogurts and soups and having frequent mouthwashes in order to replenish the dry mucosa. It may also help in the regeneration of nerve endings to improve your symptoms. Do you have any trouble swallowing? If the symptoms do not improve for another month or so or get worse, then I would suggest going back to your surgeon or physician.

I hope it helps. Best wishes.

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