Q. I have irregular periods with elevated cortisol and estradiol. Please help.

Answered by
Dr. Richa Agarwal
and medically reviewed by Dr. Vinodhini. J
This is a premium question & answer published on Jan 11, 2021

Hello doctor,

I am a 50-year-old female in good health. I am not on any medication, and I eat well. 5'4" 140 pounds. I have an irregular period, fatigue, cyclical migraine headaches, anxiety, panic attacks, and dry eyes. My basal temperature does not indicate ovulation, and the blood report came back with low vitamin D, high cortisol 22, high estradiol 613. I was on the third day of my cycle. Is this estrogen dominance, and should I use progesterone cream?

#

Hi,

Welcome to icliniq.com.

Three things are important in your case-

1) High cortisol.

2) High estradiol.

3) Low vitamin D.

The most common cause of high-level cortisol is Cushing syndrome (pituitary adenoma) and stress.

Treatment- MRI to rule out pituitary adenoma. Release your stress with the change in your lifestyle and diet.

High estradiol mainly occurs during peri-menopausal age and with a low progesterone level.

Treatment - Use progesterone cream in high doses of 400 mg/ day in two divided doses.

Low vitamin D occurs in both the above conditions.

Treatment includes direct sun light exposure. You can use Cod liver oil, fish, and cholecalciferol sachet.

Your HbA1c level is also high. It indicates you are in the prediabetic stage. So take care of your blood sugar levels. So, in my opinion, you should consult a good endocrinologist and take treatment accordingly.


Was this answer helpful?

 | 

Related Questions:
I have irregular periods with elevated cortisol and estradiol. Please help.

Thank you doctor,

Here is the picture of the rashes and the link to access my reports online for your reference.

  Read full

What causes irregular periods with pain in a 52-year-old female?

Thank you doctor,

Here is the picture of the rashes and the link to access my reports online for your reference.

  Read full

Why am I having low BP and severe intolerance to stress?

Thank you doctor,

Here is the picture of the rashes and the link to access my reports online for your reference.

  Read full

 

This is a sponsored Ad. icliniq or icliniq doctors do not endorse the content in the Ad.

Also Read Answers From:

Comprehensive Medical Second Opinion.Submit your Case

Related Questions & Answers


How to reduce levels of cortisol?

Query: Hi doctor, I am a 25 year old female. Is there any way to effectively reduce elevated cortisol and aldosterone? But, it is not Cushing's. I just have too high cortisol for the last few years and weight loss problem.  Read Full »

I have irregular periods and vaginal dryness. Can IUD be the cause?

Query: Hello doctor, I have irregular periods and vaginal dryness. I also have premenstrual spotting, followed by three days of profuse bleeding. I got an IUCD placed ten years back. I use Minoxidil 5 % for topical application, since three months, but I stopped it 15 days back. I have a history of vitamin ...  Read Full »

Are recurrent miscarriages and estradiol related?

Query: Hello doctor, I am a 29 year old woman with a history of recurrent miscarriages (3 losses, all in 5-6 weeks). I was recently diagnosed with Grave's disease (I had overt hyperthyroidism with my last miscarriage). Now my levels are in check. I had APS, ANA and thrombophilia panels, all perfect except...  Read Full »

Also Read


Sinusitis - Causes, Symptoms and Treatment
Sinusitis is the infection of the air cavities within the nasal passages. Normally, the healthy sinuses are filled with ...  Read more»
Asthma and Its Rising Incidence
This article explains about asthma and its causes. It also focuses on the benefits of starting early treatment to lead a...  Read more»
Parkinson's Disease: Historical Aspects and Current Treatment Approaches
This article discusses the historical aspects of Parkinsonism and, the evidence based approaches currently available for...  Read more»

Ask your health query to a doctor online?

Ask an Obstetrician & Gynaecologist Now

* guaranteed answer within 4 hours.

Disclaimer: All health Q&As published on this website are not intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek the advice from your physician or other qualified health-care providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.