In frozen embryo procedure, are shots necessary or will suppositories do?

Question

Hello doctor,

When doing a frozen embryo transfer cycle, is it absolutely necessary to use progesterone in oil shots or will the suppositories work the same?

Answer 1

Hello,

Welcome to icliniq.com.

How are you doing?

I am sure it is the painful pricks that is making you ask this query. It is the belief of the treating doctor, that a particular type of Progesterone is more effective. So, based on the doctor's experience, the different routes of Progesterone are preferred.

But as per studies, the effectiveness of vaginal progesterone suppositories is the highest, with a least first pass metabolism (so less is lost into the blood) and minimal side effects. So, I would advise vaginal natural micronized Progesterone 200 mg two to three times a day.

Aqueous formulations is supposed to be painless, but actually, it is painful, with an occasional hematoma or painful swelling at the site.

Vaginal application of progesterone gel, spray, or capsules are all equally effective.

Hope I have clarified your query. Do write back. All the best.

For more information consult an infertility specialist online --> https://icliniq.com./ask-a-doctor-online/infertility-specialist

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