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Does menopause delay the onset of general anesthesia?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I have been told many times following surgery that it took a long time for me to get the effect of anesthesia. I even remember some anesthesiologists getting upset with me, as it was taking so long and the attending nurses defending me.

Last time during my surgery, I spoke with the anesthesiologist before the procedure about this issue. He assured me that he had many ways to make certain that I would get the effect easily, and he could monitor it well. After the surgery, he made a point to come to me and said that I was correct. I took a long time to get the effect of anesthesia. I have been told in the past to breathe differently, or more deeply when the mask is on, but this does not make a difference.

A few years ago, when I was having a procedure, the anesthesiologist asked me if I wanted light anesthesia. I had never been asked this before. I asked her suggestion, and she said she would go with the light anesthesia. Unfortunately, I woke up during the procedure, and it was very unpleasant.

So, what are all the possible reasons for a person taking a long time to go under anesthesia?

When I was younger, this was not an issue. This began when I was approximately in my mid-40s. I am a postmenopausal woman. I am not taking any supplements or medications other than a multivitamin.

Please help.

Thank you.

Answered by Dr. Muhammad Majid Hanif

Education:

MBBS

Professional Bio:

Dr.Muhammad Majid Hanif is a highly skilled and established physician in the field of Cardiology. He listens to all the patient queries deliberately and is an expert in devising a proper treatment plan.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I have carefully reviewed your health query, and want to add that the tendency of metabolizing the drugs differ in each individual. Also, you should understand that everyone has a different level of metabolism and processing of drugs by the body.

What the body does to the drug is known as pharmacokinetics, and it governs differently in each person. Liver, lungs, kidneys, skin and heart takes drugs differently in people. This is the reason that some people feel difficult, and takes time to go under the effect of anesthesia when it comes to general anesthesia.

I hope it helps.

Thank you.

Answered by
Medically reviewed by iCliniq medical review team
Published At August 27, 2016
Reviewed At October 15, 2025

Education:

MBBS

Professional Bio:

Dr.Muhammad Majid Hanif is a highly skilled and established physician in the field of Cardiology. He listens to all the patient queries deliberately and is an expert in devising a proper treatment plan.

This doctor is not available for online consultations on the platform anymore.

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Companion

Anesthesia Onset Delay: Pharmacokinetics & Metabolism Companion

How it works

It can be concerning when anesthesia takes longer than expected. Learn about the factors that might influence how your body responds to general anesthesia.

1

Delayed
Onset

2

Pharmacokinetics
Processing

3

Individual
Metabolism

4

Organ
Function

5

Age
Factors

6

Anesthesia
Risks

This information is based on general medical guidance. It is not a substitute for professional medical advice; consult a qualified clinician.

Always consult a doctor before taking medication; self-medication carries serious health risks. Take exact prescribed doses, and never start, change, or stop treatment without medical supervision.

Dr. Muhammad Majid Hanif

Cardiology

Education:

MBBS

Professional Bio:

Dr.Muhammad Majid Hanif is a highly skilled and established physician in the field of Cardiology. He listens to all the patient queries deliberately and is an expert in devising a proper treatment plan.

This doctor is not available for online consultations on the platform anymore.

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