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Q. Bilirubin is high but other liver functions are normal. Should I worry?

Answered by
Dr. Smrita Singh
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Jan 27, 2018

Hello doctor,

I did blood tests and attached are the reports. Are they alright or do I need to investigate further?

Dr. Smrita Singh

Hematology Pathology


Welcome to

I have gone through your test results (attachment removed to protect patient identity) and the only abnormality is high direct bilirubin. Higher than normal levels of direct bilirubin in your blood may indicate your liver is not clearing bilirubin properly.

The most common causes are cirrhosis, gallbladder disease, Gilbert's syndrome, bile duct cancer or stenosis due to other causes, hepatitis, liver cancer, sickle cell disease and following chemotherapy.

You will need further tests including imaging tests to evaluate your bile duct and the liver to come to a diagnosis.

For more information consult a pathologist online -->

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Hello doctor,

Thank you for the answer. I was told by the doctor here that because my other liver functions are normal, it is nothing to be worried about. It could be Gilbert's syndrome. Is that correct?

Dr. Smrita Singh

Hematology Pathology


Welcome back to

Yes, that is a possibility since your indirect bilirubin is much higher than the direct bilirubin levels and your other liver function tests.

Your complete blood count and reticulocyte count are absolutely normal and you do not have any other disease process. The normal hematology results rule out the possibility of sickle cell disease or other hemolytic anemia which can cause high indirect bilirubin levels.

Thank you.

For further queries consult a pathologist online -->

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