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My thyroid antibody is high. Is it due to Hashimoto’s disease?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I have done all thyroid tests and am worried about the results.TSH is high at 4.56 milli international units per liter, and thyroglobulin antibodies were high at 2.8 IU/mL. TOP, T3, and T4 were normal; TPO 14 IU/mL and T4 free 0.95 ng/dl.

I am having throat pain, and I feel like my glands are swollen, along with extreme tiredness. Could this be Hashimoto's disease or cancer? I am really worried.

Please help.
Answered by Dr. Goswami Parth Rajendragiri

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

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Hello,

Welcome to icliniq.com.

Antithyroglobulin antibody can be positive in autoimmune thyroid problems. So, it can be a positive result to have Hashimoto's thyroiditis and Graves' disease. But your thyroid hormone level is within range, and TSH (thyroid-stimulating hormone) is not much elevated. So, clinical correlation is necessary with thyroid palpation and USG (ultrasound) scan.

Your throat pain can be due to thyroid inflammation or a posterior pharynx infection, which is pharyngitis. In such inflammation, glands can be enlarged due to generalized infection. Your physical examination and posterior pharynx examination should be done.

An analgesic or an antibiotic, if needed, can be prescribed. If glands get enlarged persistently, then FNAC (fine needle aspiration cytology) can be done for further diagnosis. Do not think of malignancy. Consult an otorhinolaryngologist for examination.

I hope this helps.

Thank you.

Medically reviewed by Dr. K. Shobana
Published At July 6, 2018
Reviewed At December 23, 2025

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri

Pathology

Education:

MBBS

Professional Bio:

Dr. Goswami Parth Rajendragiri is an experienced General Physician and Pathologist with extensive years of clinical expertise. He specializes in diagnosing and managing a wide range of medical conditions while providing holistic care to patients. As a Pathologist, he is skilled in performing and interpreting laboratory investigations that aid in accurate diagnosis and treatment planning. Dr. Rajendragiri is dedicated to delivering patient-focused care with a strong emphasis on preventive medicine and overall well-being.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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