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Q. TSH and TGAB are high. Could this be Hashimoto's disease or cancer?

Answered by
Dr. Parth R Goswami
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Jul 05, 2018

Hi doctor,

I have done all thyroid tests and worried about the results.TSH is high at 4.56 milli international units per liter and thyroglobulin antibodies were high 2.8 IU/mL. TOP, T3, and T4 were normal; TPO 14 IU/mL and T4 free 0.95ng/dl. I am having throat pain and I feel like my glands are swollen, along with extreme tiredness. Could this be Hashimoto's disease or cancer? I am really worried.

Dr. Parth R Goswami

Hematology Pathology


Welcome to

Antithyroglobulin antibody can be positive in autoimmune thyroid problem. So, it can be a positive result to have hashimoto's thyroiditis and grave's disease. But, your thyroid hormone level is within range and TSH (thyroid stimulating hormone) not much elevated. So, clinical correlation is necessary with thyroid palpation and USG (ultrasound) scan.

Your throat pain can be due to thyroid inflammation or from posterior pharynx infection that is pharyngitis. In such inflammation, glands can be enlarged as generalized infection. Your physical examination and posterior pharynx examination should be done. An analgesic or an antibiotic if needed can be prescribed. If glands get enlarged persistently, then FNAC (fine needle aspiration cytology) can be done for further diagnosis. Do not think of malignancy. Consult otorhinolaryngologist for examination.

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