I am 40 years old. I recently had a full panel of laboratory tests done and my platelet count was elevated as was my hs-CRP. All other reports were in optimal or normal range. My ferritin was on the lower end and my HbA1c was on the higher end of normal. I am currently being treated with low doses of T3 and T4. My thyroid is inflamed, and though a formal diagnosis of Hashimoto's is not made, it is suspected. I have high-risk HPV but my pap smear six months ago indicated everything was fine. What could be going on?
In the provided report (attachment removed to protect patient identity), the serum ferritin and hemoglobin are within the limit. A slightly elevated platelet and high CRP (C-reactive protein) can be from a temporary inflammation, in which the platelet is raised because of IL-6. Even in bleeding, the platelet can get elevated. For hypothyroidism, a regular hormonal replacement is needed, and the dose is to be adjusted according to the TSH (thyroid-stimulating hormone) level. You can discuss regarding the dose of the thyroid hormone adjustment accordingly with your treating doctor. I suggest you repeat CBC (complete blood count) after week. Consult a physician for examination and discuss your case.
The report is not alarming.
Thank you doctor,
Can being on your menstrual period raise the platelet count and hs-CRP? Also, can Hashimoto's or another auto-immune disorder affect the platelet count and hs-CRP? Should I see a cardiologist?
Hereby, I am giving you further opinion regarding your case. During the menstrual period, if there is heavy bleeding, it can be a reason for slight platelet level elevation. An autoimmune disorder can affect CRP levels, but will not affect the platelet count. Rheumatoid arthritis and SLE (systemic lupus erythematosus) can elevate CRP, but Hashimoto's thyroiditis is not a well-known cause for CRP elevation. To rule out an autoimmune thyroid disorder, investigate with a microsomal antibody test and thyroglobulin antibody test. Check serum TSH, T3 and T4. According to these thyroid reports, the further work up plan can be decided. You are right that an elevated CRP suggests a heart problem, but if the CRP is constantly elevated, then consult a cardiologist. And, if any significant cardiac history is present, then provide it. After a week, repeat CBC and CRP. If needed you can consult a physician for an examination. Provide any other complaints, if any, for giving further comments. Your HbA1c is also within the limit with a normal sugar level.
I hope your concern is solved.
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