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Why is Aspirin given for high hemoglobin and RBC count?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I am a 40-year-old male. My hemoglobin was 18.3 g/dL (gram per deciliter), but it has come down to 17.7 g/dL in the last two months. My RBC count varies between 6.1 and 6.27 now, and my PCV is 51.9 percent. I am taking mini Aspirin as suggested by my doctor.

Do I have any reason to worry?

Please guide.

Thank you.

Hi,

Welcome to icliniq.com.

Your hemoglobin level, RBC (red blood cells), and PCV (packed cell volume) are high. The lymph node, liver, and spleen need to be clinically examined.

Do you have a history of dizziness, weakness, and stroke?

High levels of RBC and hemoglobin can cause blood clots and can lead to vascular complications like stroke. This is the reason your doctor gave you Aspirin.

You are at risk of polycythemia vera, and it has to be ruled out by a bone marrow study or molecular testing for JAK2 gene mutation.

Phlebotomy might be needed to reduce RBC mass. Consult your physician or a nearby hematologist for examination and further workup.

I hope this information helps provide some insight into your symptoms.

Please do not hesitate to reach out if you have any further questions or concerns.

Do follow up whenever needed.

Let me know if I can assist you further.

Thank you.

Medically reviewed byiCliniq medical review team

Published At March 26, 2017
Reviewed AtApril 15, 2026

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