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Are HIV tests conclusive between 39 and 105 days?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello, Doctor,

I had sex with a sex worker. I took PEP (post-exposure prophylaxis) medicine for the first three days after exposure. After 39 days, I took a combo test, and after 58 days, a fourth-generation HIV duo ultra antibody and antigen test. The results were negative. After 87 days, my antibody test was negative, and after 105 days, the HIV 1 and 2 CMIA (chemiluminescent microparticle immunoassay) combo antigen and antibody test was negative.

Are all the test results 100% conclusive?

Kindly advise.

Answered by Dr. Davie Wong

Hello,

Welcome to icliniq.com.

I understand your concern. A fourth-generation HIV (human immunodeficiency virus) antibody test can detect HIV infection 15 to 20 days after exposure. If your test remains negative 105 days after exposure, you can be confident that you do not have HIV. The accuracy of fourth-generation HIV tests is very close to 100%.

I hope this helps.

Thank you.

Patient's Query

Hello, Doctor,

Thank you for the answer.

Can using PEP medication for three to four days affect the duration?

Kindly help.

Answered by Dr. Davie Wong

Hello,

Welcome back to icliniq.com.

Taking PEP (post-exposure prophylaxis) medicine for three days will not affect the results. However, if you had contracted HIV, your antibody test would have come positive by now.

I hope this helps.

Take care.

Answered byDr. Davie Wong

Medically reviewed byiCliniq medical review team

Published At August 21, 2022
Reviewed AtNovember 19, 2025

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