Q. HIV 1 and 2 are nonreactive 28 days after exposure. Should I repeat it later?

Answered by
Dr. Rakesh Kumar Bahunuthula
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Nov 18, 2017

Hello doctor,

HIV 1 and 2 are nonreactive in the tri-dot test after 28 days of exposure. Should I repeat the test again for confirmation?



Welcome to icliniq.com.

  • Tri-dot is a third generation test for HIV (human immunodeficiency virus).
  • HIV infection has a window period of one to three months during which these test results may be false negative. According to WHO (world health organization), all the test results are considered conclusive 12 weeks after the last exposure.
  • However, fourth generation HIV tests are considered to be accurate one month after the last exposure.
  • Hence, you can either repeat tri-dot after three months or go for a fourth generation combo test one month after the last exposure to confirm the result.

For more information consult an HIV AIDS specialist online --> https://icliniq.com./ask-a-doctor-online/HIV-AIDS-specialist

Thank you doctor,

HIV 1 RNA RT PCR is also negative 14 days after exposure. Is this conclusive? Please help.



Welcome back to icliniq.com.

  • The test is almost 99 percent accurate by two weeks. However, as per WHO guidelines, we advise retesting after a baseline test.

For further queries consult an HIV AIDS specialist online --> https://icliniq.com./ask-a-doctor-online/HIV-AIDS-specialist

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