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Q. HIV 1 and 2 are nonreactive 28 days after exposure. Should I repeat it later?

Answered by
Dr. Rakesh Kumar Bahunuthula
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Nov 18, 2017 and last reviewed on: Sep 28, 2022

Hello doctor,

HIV 1 and 2 are nonreactive in the tri-dot test done after 28 days of exposure. Should I repeat the test for confirmation?

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#

Hello,

Welcome to icliniq.com.

Tri-dot is a third-generation test for HIV (human immunodeficiency virus).

HIV infection has a window period of one to three months, during which these test results may be false negative. According to WHO (world health organization), all the test results are considered conclusive 12 weeks after the last exposure. However, fourth-generation HIV tests are considered accurate one month after the last exposure. Hence, you can repeat the tri-dot after three months or go for a fourth-generation combo test one month after the last exposure to confirm the result.

Thank you doctor,

HIV 1 RNA RT PCR is also negative 14 days after exposure. Is this conclusive? Please help.

#

Hello,

Welcome back to icliniq.com.

The test is almost 99 percent accurate by two weeks. However, as per WHO guidelines, we advise retesting after a baseline test.


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