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What causes fever, diarrhea and knee pain in HIV -ve person?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I had exposure to HIV 10 months back, and after that, I got myself tested. Rapid ICT and particle agglutination after six weeks. HIV Ag and Ab screening S/CO = 0.18, CMIA Method after eight weeks. Serum Electrochemiluminescence or Immunoassay method after 16 months. All tests reported negative. But I have been having symptoms of fever, loose motion, and pain in knee joints. Can you advise further action?

Regards.

Hi,

Welcome to icliniq.com.

Thanks for the query.

I can understand your concern. According to your statement, you have been suffering from constant loose motion, fever, and joint pain.

HIV antibodies: HIV 1 and HIV 2 are non-reactive three months back. Again, HIV for rapid ICT and partial agglutination are non-reactive, and the final status is negative seven months before. HIV antigen or antibody screening is non-reactive on two months back.

Well, you are free from HIV infection. Persistent diarrhea, fever, joint pain, etc., may result from some underlying diseases other than HIV infection such as enteric fever, whipple disease, crohn's disease, lyme disease, reactive arthritis, etc.

Treatment depends on causes. It would help if you underwent some investigations like:

  1. Widal test.
  2. Stool routine microscope.
  3. Culture and sensitivity.
  4. Colonoscopy.
  5. Sigmoidoscopy.
  6. Tissue biopsy.
  7. PCR (polymerase chain reaction) test for Tropheryma whippleii.
  8. Aspiration of fluids from joints for analysis.
  9. CT (computed tomography) abdomen,
  10. ELISA (enzyme linked immuno sorbent assay) for Borrelia burgdorferi.
  11. Western blot.
  12. CRP (C-Reactive Protein), etc to detect the underlying causes for your present sufferings and then treat them accordingly.

In case of any other query, ask me.

Patient's Query

Hi doctor,

Thank you for your reply.

Correction to your reply: the second test was five months ago, eight weeks after exposure, and it is not two months back. I also noticed a slight white texture on my tongue, but it does not pain.

Hi,

Welcome back to icliniq.com.

Thanks for joining us again. Your recent test has shown non-reactive. That is enough for confirming that you are now totally free from HIV infections. White patches on the tongue may suggest fungal or yeast infection, most probably oral candidiasis by Candida albicans.

Apply Miconazole gel or paste on your tongue and oral cavity two to three times daily with taking B-complex supplements. I hope they will help to subside your oral infection caused by fungus. Please do the investigations mentioned above to find out the causes which are responsible for present sufferings. If any other query, knock me, and I will try to reply to you further.

Medically reviewed byDr. Preetha. J

Published At October 30, 2020
Reviewed AtJuly 17, 2025

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