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Does caffeine cause my persistent nausea and anxiety?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I have had persistent nausea for roughly 15 months now. I remember it began on a holiday when I had drunk coffee and ended up with anxiety symptoms.

I have had many tests done, and an endoscopy found eosinophilic esophagitis (basically, esophagitis caused by an allergy). I have been treated with a PPI, which appears not to be helping, and have also been prescribed Lovan (Fluoxetine). I am currently one week into taking these tablets and have recently cut out gluten and dairy to see if the allergy was from these foods.

The doctor did a RAST test, which showed a class 0 allergy to all main food groups, including wheat and milk. So I have just started eating them again. I have just drunk my first coffee in about a week and had severe panic symptoms and a tight throat, which I have never experienced before. I would like to know if a caffeine allergy is likely and if it could be the cause of all these problems. I used to drink coffee fairly regularly and never quite felt great off it, but it never seemed to worsen the nausea.

Please help.

Thank you.

Answered by Dr. Amol Kumar Wasudeorao Diwan

Education:

MBBS

Professional Bio:

Dr. Amol Kumar Wasudeorao Diwan is a qualified Specialist in Pulmonary Medicine, Tuberculosis, and Respiratory Diseases with extensive years of clinical experience. He has a vast network of professional contacts in the medical field, an outstanding ability to provide healthcare with an emphasis on holistic approach, treating the patients as a physical, emotional, and social being, has an excellent bedside manner, and an admirable ability to establish rapport with the patient. He also has exceptional skills in imparting health related teachings for a complete and speedy recovery of his patients and has an incomparable critical thinking and analytical skills.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I read your query and understand your concern.

After going through your history, it is very clear that what you described are two totally different issues. One thing is eosinophilic esophagitis (an allergic inflammatory condition of the esophagus that involves eosinophils), and the second is caffeine sensitivity. I used the word "sensitivity" for caffeine because it is different from caffeine allergy.

What you are suffering from now may be caffeine hypersensitivity, as there are no other allergic symptoms associated with panic attacks. Even if you were having coffee before, you may become hypersensitive to coffee now.

The treatment for it is to avoid coffee and see the difference. Some oral steroid sprays like Flovent (fluoxetine) are also advised by gastroenterologists to prevent the side effects of long-term oral steroids. It is very difficult to differentiate between caffeine sensitivity and allergy based on clinical examination. For that, you need to do a skin prick test. Finally, avoidance is the best strategy for treating caffeine sensitivity.

Please let me know if you want more help.

Thank you.

Medically reviewed by Dr. Divya Banu M
Published At November 24, 2019
Reviewed At October 29, 2025

Education:

MBBS

Professional Bio:

Dr. Amol Kumar Wasudeorao Diwan is a qualified Specialist in Pulmonary Medicine, Tuberculosis, and Respiratory Diseases with extensive years of clinical experience. He has a vast network of professional contacts in the medical field, an outstanding ability to provide healthcare with an emphasis on holistic approach, treating the patients as a physical, emotional, and social being, has an excellent bedside manner, and an admirable ability to establish rapport with the patient. He also has exceptional skills in imparting health related teachings for a complete and speedy recovery of his patients and has an incomparable critical thinking and analytical skills.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Divya Banu M is a dedicated Dental Surgeon with valuable clinical experience. She specializes in the diagnosis, prevention, and treatment of various diseases and conditions affecting the oral cavity. With a gentle and patient-centered approach, she is committed to promoting oral health and enhancing smiles through quality dental care. Her areas of expertise include restorative dentistry, preventive dental care, and cosmetic dental procedures.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Amol Kumar Wasudeorao Diwan is a qualified Specialist in Pulmonary Medicine, Tuberculosis, and Respiratory Diseases with extensive years of clinical experience. He has a vast network of professional contacts in the medical field, an outstanding ability to provide healthcare with an emphasis on holistic approach, treating the patients as a physical, emotional, and social being, has an excellent bedside manner, and an admirable ability to establish rapport with the patient. He also has exceptional skills in imparting health related teachings for a complete and speedy recovery of his patients and has an incomparable critical thinking and analytical skills.

This doctor is not available for online consultations on the platform anymore.

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