What could be the reason for my IVF failure?

Hello doctor,

I have not conceived in 11 years. I have PCOS and low AMH, and I had adhesiolysis surgery a few months before going for IVF. Currently on medicines like Inositol, Suresitol (one sachet daily), Femgold, Folcure-5, Metformin, supplements like multivitamins, vitamin D, biotin, omega-3, vitamin E, vitamin C, and coenzyme Q10. I am also trying to improve my lifestyle.

I am looking for a second opinion on the treatment I am taking for infertility. I had one failed IVF-ICSI. Out of seven eggs, only two were fertilized. One stopped after fertilization, another slowed down or stopped after three cells. My husband’s sperm were normal for the treatment, with DNA fragmentation around 19 % before IVF. After it failed, our doctor suggested doing a karyotyping test for both of us.

My husband’s report was normal, but mine showed something like 46 XX and 22ps+. I want to know what this karyotype result concludes? What are our chances of success if we go for another round of IVF? My karyotyping result might explain failed fertilization or embryo formation. Does this conclude that my eggs are not viable at all? We cannot go for donor eggs or sperm due to personal reasons.

I would highly appreciate your honest opinion on this.

Thanks in advance.