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How to treat fertility issues caused by irregular ovulation?

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Patient's Query

Hello doctor,

I am a 23-year-old woman seeking help for fertility. I have slightly raised prolactin levels, but my progesterone and estrogen levels are normal. I am using a ovulation monitor, which indicates my periods are 33 days long. Although my estrogen levels rise, I do not experience luteinizing hormone surge to ovulate. Some people have recommended Clomifene. I would like to know what you would recommend?

Hello,

Welcome to icliniq.com.

I read your query and understood your concern. Firstly, I would like to inform you that, if prolactin is high, as often happens during breastfeeding, there will be no rise or fall of estrogen and progesterone. This is the reason you may experience no periods and ovulation during breastfeeding, resulting in lactational amenorrhea. If you are having periods within a 33-day cycle, it indicates ovulation is occurring. A menstrual cycle frequency of 28 with variation of seven days is considered normal, and there might not be a need for any intervention. One issue I observed is your weight. Weight and cholesterol can be converted into estrogen hormones, and the resulting imbalance can disrupt the smooth curve of hormonal changes, affecting ovulation hormones. Your expected weight range is around 114 to121 lbs . Once you reduce your weight to this normal range, you may not need any medication to regulate your periods or enhance fertility, and your pregnancy journey could be healthier. To achieve weight reduction, I suggest you avoid fasting, junk food, fast foods, and red meat. Cut down on snacks between meals and opt for low-calorie, high-protein foods. Engage in regular exercises, especially focusing on the waist and hip areas. Activities like aerobics, yoga, brisk walking with swinging your arms well, and a weight reduction rate of four to eight pounds per month are recommended. Remember, gradual weight loss is easier to maintain. As soon as you shed a few pounds, you will likely notice positive changes. The tablet containing Clomifene50 to 100 mg can be helpful. It suppresses estrogen, thereby increasing follicle stimulating hormone and follicle development, enhancing the chances of ovulation. I suggest you undergo following investigations:

For Males:

  1. Semen analysis (at least two times, done four weeks apart, preferably in an infertility center).
  2. Blood sugar tests.

For Females:

  1. Blood sugar tests.
  2. Thyroid profile.
  3. Ultrasound scans to evaluate uterus, ovaries, and adnexa.
  4. Additionally, confirm tubal patency, which is crucial. Tubes are the connection between the uterus and ovaries (the bridge where sperm meets the egg to form a baby), and this small tube can get blocked easily. Confirm tubal patency through procedures like hysterosalpingography (X-ray with dye), sonosalpingography (scan with dye), or laparoscopy.

If all these tests are conducted and found to be normal, there is no reason a pregnancy cannot happen. I suggest you consult a specialist, talk with them, and take the medications with their consent. I hope this has helped you. Kindly follow up if you have more doubts.

Thank you.

Medically reviewed byiCliniq medical review team

Published At January 5, 2024
Reviewed AtJune 27, 2024

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