HomeAnswersPsychiatrymaniaWhat is the treatment of mania?

How can mania be treated?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

Dr. Divya Banu M

Published At December 29, 2019
Reviewed AtMarch 14, 2024

Patient's Query

Hello doctor,

What is the treatment of mania?

Please help.

Hi,

Welcome to icliniq.com.

The treatment option for mania is many including antipsychotic such as Arpizole and other antipsychotic, and mood stabilizing drug such as Sodium valproate or Lithium and/or Carbamazepine. The choice of drug depends upon the patients choice and side-effects profile of drug. So, please let me know exactly what you want.

Thank you.

Patient's Query

Hello doctor,

Thank you for your reply.

What should be the effective dose of Arpizole for mania and will it be sufficient without mood-stabilizer?

Please help.

Hi,

Welcome back to icliniq.com.

Arpizole is used in dose of 10 to 30 mg for mania and it may be sufficient for a few cases and may require other mood-stabilising drug in other cases. It depends upon person to person. However, lower doses can be used if person is showing good response, others need to increase the doses to 30 mg per day. If you are stable on 7.5 mg of Arpizole then it is good, otherwise need to increase the doses first and then add other drug.

Hope it helps.

Thanks and regards.

Patient's Query

Hello doctor,

Thank you for replying.

I consulted today evening with doctor and he increased Arpizole 7.5 mg to 10 mg and Lithium 300 twice daily for twenty days and then follow again. But my daughter is reluctant to take Lithium and is saying that I will take only Arpizole10 mg till exams. I have tried to convince her but she is not listening. Can Arpizole 10 mg also work as mood-stabilizer as Lithium does?

Please help.

Hi,

Welcome back to icliniq.com.

Lithium is a good drug along with Arpizole. Why your daughter is reluctant to take Lithium, any reason she is providing? Arpizole 10 mg is effective in many patients but not in all. Arpizole in 10 mg may not be as effective as Lithium but it is effective in many cases. If she is not agreeing to take Lithium then ask your doctor to follow up earlier with only Arpizole and if needed, doses of Arpizole can be increased and that may be helpful. This will probably increase her compliance of medicine as her wishes to take only Arpizole are listened. You can wait for a week on Arpizole 10 mg and see the response and visit your psychiatrist more frequently to assess the response to Arpizole alone.

Hope it helps.

Thank you.

Patient's Query

Hello doctor,

Now my daughter is convinced and taking Lithium 300 twice since Saturday along with Arpizol 10. For how many months, she should take these medicines. And another question is that if someone one take Lithium for long periods then can it cause depression due to hypothyroidism. So please suggest atypical antipsychotics alone in optimum dosage as a prophylactic in place of lithium as mood stabilizer or to control bipolar disorder.

Please help.

Hi

Welcome back to icliniq.com.

Lithium should be continued for at least 12 months and if there are no symptoms after this period then Lithium can be tapered slowly over a month and then can be stopped. Yes, Lithium can indeed cause hypothyroidism so you need to check your thyroid hormone levels regularly along with renal function also.

If you think that compliance is an issue then avoid lithium. A sudden stop of Lithium can cause manic symptoms to reappear. Among atypical antipsychotics, Arpizole comparatively has lesser metabolic side effects. So as of now follow your psychiatrist's advice.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ramchandra Lamba
Dr. Ramchandra Lamba

Psychiatry

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