Is brisk reflex a sign of PPMS?

Hi,

Welcome to icliniq.com. I have gone through your query with diligence and would like you to know that I am here to help you. Brisk reflexes mean that the signals to the spinal cord are reduced. This can be due to any reasons. PPMS - primary progressive multiple sclerosis is one of the reasons for brisk reflexes. In other words, if there is a brisk reflex, thenit does not mean that it is only PPMS. It can be due to any reasons. PPMS can present with brisk reflex or can also present with normal reflexes. With brisk reflexes alone, we can neither confirm nor rule out PPMS. We need to do a thorough evaluation and add all the points together and then decide.

Hi,

Welcome back to icliniq.com. As per theory, exercise-induced weakness is a characteristic symptom of multiple sclerosis (MS). The weakness is of the upper motor neuron type and is usually accompanied by other pyramidal signs such as spasticity, hyperreflexia and Babinski's' signs (plantar response). Occasionally, a tendon reflex may be lost (simulating a lower motor neuron lesion) if an MS lesion disrupts the afferent reflex fibers in the spinal cord. Primary progressive multiple sclerosis (PPMS) is less likely with subdued reflexes. If we do an magnetic resonance imaging (MRI), then we can rule out with certainty that this is not PPMS.

Hi,

Welcome back to icliniq.com. No, it does not depend on age. Your subdued reflexes make primary progressive multiple sclerosis (PPMS) less likely. Yes, if you were to get an magnetic resonance imaging (MRI) brain and spine, and if that was clear, then it would mean that you do not have PPMS.