I am 67. I take 120 mg Diltiazem twice daily. It was originally given to me because undiagnosed sleep apnea had caused "borderline hypertrophy of the heart" I now also take it because I have a tachycardia once or twice a year. It was not given to me for high blood pressure. When a doctor takes my blood pressure, sometimes it is normal, sometimes it is up to say 140/90, and very rarely it may read just slightly higher. I have been a very light sleeper for a long time. I have just heard that older people produce less melatonin. I checked online and found that there is some possibility of drug interaction between diltiazem and melatonin, but I don't know if it's serious. How concerned should an average male in my situation be about starting to take 5 mg of melatonin bed time? Currently I am on clonapin, prilosec, testosterone, and simvastatin.
1. Today, a new unique method for accurate laboratory diagnosis of melatonin deficiency has appeared, based on the calculation of the level of its free fraction in saliva (steroid profile in saliva). This method allows you to determine the free fractions of not only melatonin, but also other steroid hormones (free testosterone, cortisol, cortisone, progesterone, dehydroepiandrosterone, androstenedione) and has a high measurement accuracy (free melatonin levels are best measured at night - during the physiological peak of its secretion by the pineal gland)/
2. You also need to conduct a study of the brain, namely the pituitary gland and the pineal gland. On MRI, we will see a pituitary adenoma or calcification of the pineal gland.
3. For a detailed understanding, I recommend that you do a complete blood count and biochemistry.
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