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Why do I have persistent GERD and weight loss?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I am 54 years old with a weight of 136lbs and a height of five feet. I have had these symptoms for the past five months. I have anorexia with loss of appetite. I have dyspepsia with difficulty in swallowing food and water. I have an acidic burn with an outcome of mucin. I have GERD. I have a sleep disturbance within an interval of two to three hours of sleep. I have lost weight from 158 to 136 lbs within three months. I have a positive result for Helicobacter pylori infection. My upper GI endoscopy showed pan gastritis. I have a past history of piles, and a feeling of a lump in the throat after eating. I suffered from a head injury in the last month. I have weakness and dizziness now. Currently, I am taking Aristozyme for 60 days, three times a day, with Wel liv syrup for 30 days, two times a day. I am taking all these tablets for 15 days. Again, I was advised to take Vegazold for 60 days once daily, and Happi for 60 days once daily. I am taking it for 30 days.

Kindly guide.

Hi,

Welcome to icliniq.com.

I have gone through the attached report (attachment removed to protect patient identity). The important things are pangastritis, solitary rectal ulcer, and anemia. As you have persistent problems related to GERD and gastritis, these can be resolved by taking drugs. I suggest you take a combination of Domperidone and Pantoprazole. This helps with GERD. At this age, you seem to have significant weight loss, and it cannot be neglected. I want to know whether you have anorexia or a fear of eating due to gastritis. You have not mentioned your condition regarding blood pressure, ECG (electrocardiogram), and chest X-ray. I am concerned about your weight loss. At this age, it can be due to malignancy. Please mention in detail about your menstrual history. I advise you to do a breast examination by yourself or by consulting a surgeon to check for any lumps. I also advise you to discuss with your doctor about adding a drug called Escitalopram (SSRI). Please review the above.

I hope this helps.

Thank you.

Patient's Query

Thank you, doctor,

I took a combination of anti-gastric (Omido) and antiemetic drugs for a month, but no significant relief was observed. I have 130/83 mmHg of blood pressure and a pulse rate of 74 beats per minute. I have anorexia without any fear of eating. I have not done an ECG. I have attached my chest X-ray. I do not have any breast lumps. Kindly advise the necessary tests to be done for weight loss. I have attached my biopsy report. My menopause started ten years ago. Please tell me the necessity of taking an SSRI. I have mucin coming out of my nose, especially while eating. My eruption is getting worse day by day after eating food, and it can occur at any time. Sometimes, I have mucin coming out through my mouth. After taking medication, the symptoms decrease, and GERD also decreases. I have continuous sleep disturbance. Kindly suggest another requisite department for a consult if required.

Hi,

Welcome back to icliniq.com.

Everything seems to remain related to the acid-peptic disease. The solitary rectal ulcer has to be taken into consideration at present. Your report does not suggest any sign of a malignant ulcer. But we should mark it and have a follow-up after six months. I do not find any reason to do more investigations and to consult another specialist for this problem, as you were already evaluated by many specialists. You should know that sleep disturbances and stress increase acid peptic disease and GERD (gastroesophageal reflux disease). So I want to make you sleep peacefully. I do not mind adding a drug to your sleep problems. If you have a good sleep, you will notice a lot of improvement in the symptoms. SSRI (selective serotonin reuptake inhibitors) is used to treat depression, and they have other roles to play in other diseases also. Taking Amitriptyline is effective against acid peptic disease. Some people get good sleep by taking an SSRI. If it does not help, you can take Etizolam.

I hope I am able to solve your query. If you have any other queries, please ask me.

Thank you.

Medically reviewed byDr. Sneha Kannan

Published At September 2, 2020
Reviewed AtDecember 9, 2025

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