What are the tests to identify the cause of recurrent miscarriages?

Hi,

Welcome to icliniq.com.

I read your query and understand your concern.

Treatment will be dependent on the cause of recurrent abortions. In about 30-50 % of cases, the cause is undetectable. I would suggest you to do the following investigations.

1. USG (ultra sonogram) pelvis scan.

2. Thyroid profile.

3. APLA (Antiphospholipid antibodies) test.

4. TORCH (toxoplasmosis, rubella cytomegalovirus, herpes simplex, and HIV) test.

5. CBC (complete blood count).

6. Urine routine microscopy test.

I would also suggest you start taking Progesterone and Aspirin whenever pregnancy occurs to prevent miscarriage. Consult your specialist doctor, talk to them, and then take the medications.

Do you have a family history of congenital anomalies, or did you and your spouse have a consanguineous marriage?

Thank you.

Hi,

Welcome back to icliniq.com.

Based on the karyotype study, the presence of a pericentric inversion in chromosome 9 could potentially contribute to the abortions, but it cannot be confirmed as the sole reason. As I have already mentioned, I would suggest you undergo additional investigations such as APLA, TORCH test, blood glucose levels, serum progesterone, USG scan, and, if there is a family history of thromboembolism, BT, and CT (bleeding time and clotting time). These are essential investigations in cases of recurrent abortions.

Donor sperm is typically used when there are abnormalities in the partner's sperm. IVF (in-vitro fertilization) procedures, on the other hand, have a success rate of around 50%, which may require multiple attempts. If you are able to conceive naturally, there is no need to pursue IVF (although there might be a higher risk of abortion compared to natural conception).

If considering IVF, it is important to note that the cost for one IVF cycle ranges from approximately 50,000 to 1 lakh (Indian currency). Therefore, it is recommended to undergo a comprehensive work-up before deciding to proceed with IVF.

After an abortion, it is advisable to wait at least three months before attempting pregnancy again, as the body requires time to recover. Additionally, I would suggest you start taking Folic acid tablets at least three months prior to planning a pregnancy.

Thank you.

Hi,