What are the possible causes of muscle twitching, leg pain, and heaviness?

Hi,

Welcome to icliniq.com.

I understand your concern.

How old are you now, and what medications are you currently taking? Do you have medical conditions such as diabetes, cancer, or renal and liver problems? Do you drink a lot of alcohol? Are you exposed to pesticides? I understand you had an EMG (electromyography). How about NCV (nerve conduction velocity) or nerve conduction test? Is it normal also? Based on the information, you have neuropathy, but we have to investigate the etiology. I am thinking of small fiber neuropathy if NCV is normal. Kindly also get serum vitamin B12, ESR (erythrocyte sedimentation rate), and C-reactive protein. Meanwhile, you can take Amitriptyline 25 mg daily at night and Alpha lipoic acid once a day, as tolerated.

I hope this information will help you.

Thanks.

Hi,

Welcome back to icliniq.com.

I understand your concern.

Campylobacter infection is associated with Guillain barre syndrome, a demyelinating nerve problem. The temporal profile is important which came first. So the test came first and revealed normal results, then after a few weeks, you had pain and weakness in the legs. It would help if you had a follow-up study of NCV (nerve conduction velocity). It is usually painless for ALS (amyotrophic lateral sclerosis), so it is unlikely the cause of your symptoms. The best thing is EMG (electromyography), primarily if the presentation focuses more on muscle twitching and atrophy. Multiple sclerosis usually presents with focal weakness. It is stroke-like. Hyperreflexia is also seen, which is not seen with you.

I hope this information will help you.

Thanks.

Hi,

Welcome back to icliniq.com.

I understand your concern.

Guillain barre syndrome is under neurology, so that you can go to your neurologist for further evaluation. Melatonin is for sleep, Pregabalin is for neuropathic pain, and Clonazepam is for rest and probably to calm any anxiety. They are for symptomatic relief, so yes, they can help. For chronic gastrointestinal infections, it is best to evaluate vitamin B12 in case of malabsorption problems. Vitamin B complex would be a regimen but should be pulled out if serum vitamin B12 is normal or high. If you have night chills and fever, please have an X-ray of the chest. Include CBC (complete blood count, ESR (erythrocyte sedimentation rate), C-reactive protein, serum sodium, potassium, calcium, and magnesium.

I hope this information will help you.

Thanks.

Hi,

Welcome back to icliniq.com.

I understand your concern.

Yes, what you feel may be related to your gastrointestinal symptoms. It should have resolved if you had Guillain barre syndrome, and it had been weeks or months. But if not, it may have converted into its chronic form, called CIDP (chronic inflammatory demyelinating polyneuropathy). However, I need a follow-up NCV (nerve conduction velocity) to confirm my impression. IVIG (intravenous immunoglobulin) and plasmapheresis may be the treatment. It is also best to see an infectious disease specialist or a gastroenterologist for chronic stomach symptoms. We can have other differentials such as celiac disease, irritable bowel syndrome, and whipples.

I hope this information will help you.

Thanks.