HomeAnswersPsychiatryocdDid my OCD and anxiety worsen because I switched over from the tablet Escitalopram to Clomipramine?

Will the OCD subside if the patient changes his medication from Escitalopram to Clomipramine?


The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

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Published At June 28, 2022
Reviewed AtSeptember 11, 2023

Patient's Query

Hello doctor,

My anxiety increased after I switched over from the tablet Escitalopram to Clomipramine. I have been taking Clomipramine tablets for two weeks, and my obsessive-compulsive disorder (OCD) has worsened. Currently, I am taking tablets Anafranil 150 mg and Amisulpride 150 mg. Did my OCD worsen because I changed my medications? Will my OCD subside?


Welcome to icliniq.com.

I can understand your situation. However, I humbly request that once you are stable on some specific medication, you must not change them because it is difficult to switch to another medicine and get stable. Sometimes you might take a few weeks to get stable. So, I suggest you switch to your previous medications, that is, tablet Escitalopram and Amisulpride with the same doses.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Vishal Anilkumar Gandhi
Dr. Vishal Anilkumar Gandhi


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